Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADW18879.1PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: cyh:Cyan8802_0020 PfkB domain protein; PFAM: PfkB domain protein; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase. (288 aa)    
Predicted Functional Partners:
ADW16491.1
COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR011858: IPR006062; KEGG: dak:DaAHT2_2293 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; SPTR: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, eukaryotic; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, eukaryotic type.
  
    0.839
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.799
ADW17909.1
COGs: COG0605 Superoxide dismutase; InterPro IPR019831: IPR019832: IPR001189: IPR019833; KEGG: efa:EF0463 superoxide dismutase, Mn; PFAM: Manganese/iron superoxide dismutase-like; PRIAM: Superoxide dismutase; SPTR: Superoxide dismutase; PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain.
    
 
 0.778
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.737
ADW16866.1
UDP-N-acetylmuramyl-tripeptide synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterProIPR000713: IPR013221: IPR004101: IPR005761: IPR 005863; KEGG: dps:DP2901 putative bifunctional UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase/UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimel [...]
  
   0.727
ADW16522.1
Haloacid dehalogenase domain protein hydrolase; COGs: COG0546 phosphatase; InterPro IPR005834; KEGG: cyn:Cyan7425_0848 haloacid dehalogenase domain protein hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Slr0586 protein.
 
     0.665
rpsK
SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
   
   0.651
ADW17638.1
Phospholipid-binding protein, PBP family; COGs: COG1881 Phospholipid-binding protein; InterPro IPR005247: IPR008914; KEGG: eba:ebA6371 hypothetical protein; PFAM: PEBP family protein; SPTR: Putative uncharacterized protein; PFAM: Phosphatidylethanolamine-binding protein; TIGRFAM: Raf kinase inhibitor-like protein, YbhB/YbcL family.
  
  
 0.600
ADW16766.1
KEGG: kol:Kole_0455 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.540
ADW17419.1
Thioredoxin domain-containing protein; InterPro IPR017936: IPR013766; KEGG: dal:Dalk_4731 thioredoxin domain protein; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin domain protein; PFAM: Thioredoxin.
   
 
 0.530
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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