STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18879.1PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: cyh:Cyan8802_0020 PfkB domain protein; PFAM: PfkB domain protein; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase. (288 aa)    
Predicted Functional Partners:
ADW16766.1
KEGG: kol:Kole_0455 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.861
ADW16491.1
COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR011858: IPR006062; KEGG: dak:DaAHT2_2293 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; SPTR: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, eukaryotic; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, eukaryotic type.
  
  
 0.852
ADW16522.1
Haloacid dehalogenase domain protein hydrolase; COGs: COG0546 phosphatase; InterPro IPR005834; KEGG: cyn:Cyan7425_0848 haloacid dehalogenase domain protein hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Slr0586 protein.
 
   
 0.671
ADW18964.1
Succinate semialdehyde dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160: IPR010102; KEGG: rce:RC1_1593 succinate-semialdehyde dehydrogenase (NADP+); PFAM: Aldehyde Dehydrogenase; SPTR: Succinate-semialdehyde dehydrogenase (NADP+); TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase.
  
 
 0.656
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.646
ADW18043.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterProIPR020845: IPR009081: IPR006163: IPR000873: IPR 002123; KEGG: ppr:PBPRB0014 acyltransferase family protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: Hypothetical acyltransferase family protein; PFAM: Phosphopantetheine attachment site; Acyltransferase; AMP-binding enzyme; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
  
 0.624
ADW18688.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR002123: IPR020845: IPR000873; KEGG: dar:Daro_0402 AMP-dependent synthetase and ligase:phospholipid/glycerol acyltransferase; PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: AMP-dependent synthetase and ligase:Phospholipid/glycerol acyltransferase; PFAM: Acyltransferase; AMP-binding enzyme; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
 
 0.605
ADW19071.1
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: dps:DP0795 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Probable ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
  
 
 0.595
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.587
ADW17730.1
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: dak:DaAHT2_0812 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
  
 0.568
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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