STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpAATP-dependent Clp protease ATP-binding subunit ClpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR004176: IPR003959: IPR013093: IPR019489: IPR 001270: IPR018368: IPR003593: IPR013461; KEGG: dak:DaAHT2_2492 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease, ATP-binding subunit clpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino termi [...] (756 aa)    
Predicted Functional Partners:
ADW18902.1
ATP-dependent Clp protease adaptor protein ClpS; COGs: COG2127 conserved hypothetical protein; InterPro IPR003769; KEGG: dak:DaAHT2_2499 ATP-dependent Clp protease adaptor protein ClpS; PFAM: ATP-dependent Clp protease adaptor protein ClpS; SPTR: ATP-dependent Clp protease adaptor protein ClpS; PFAM: ATP-dependent Clp protease adaptor protein ClpS.
 
 
 0.990
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.984
ADW18184.1
COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907: IPR018215; KEGG: dps:DP2538 ATP-dependent Clp protease, proteolytic subunit (ClpP); PFAM: peptidase S14 ClpP; PRIAM: Endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP.
 
 
 0.962
ADW16386.1
KEGG: aco:Amico_1120 peptidase U35 phage prohead HK97; SPTR: Peptidase U35 phage prohead HK97.
  
 
 0.956
ADW17097.1
GrpE protein; COGs: COG0576 Molecular chaperone GrpE (heat shock protein); InterPro IPR000740; KEGG: dak:DaAHT2_0057 GrpE protein; PFAM: GrpE protein; SPTR: Protein grpE; PFAM: GrpE.
  
 
 0.883
ADW17632.1
Response regulator receiver protein; COGs: COG0466 ATP-dependent Lon protease; InterProIPR001789: IPR003959: IPR003593: IPR001984: IPR 008268; KEGG: dma:DMR_10810 ATP-dependent protease Lon; PFAM: AAA ATPase central domain protein; response regulator receiver; SMART: response regulator receiver; AAA ATPase; SPTR: ATP-dependent protease Lon; PFAM: Response regulator receiver domain; ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La.
  
 
 0.864
ADW18122.1
COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterProIPR003095: IPR012724: IPR018253: IPR001623: IPR 001305: IPR002939; KEGG: dps:DP1482 chaperone protein DnaJ; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; DnaJ central domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Chaperone protein dnaJ; TIGRFAM: chaperone protein DnaJ; PFAM: DnaJ domain; DnaJ central domain (4 repeats); DnaJ C terminal region; TIGRFAM: chaperone protein DnaJ.
  
 
 0.860
groS
Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
 
 0.845
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 
 0.841
ADW17196.1
KEGG: tau:Tola_0702 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.826
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.