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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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ADW18905.1Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: dak:DaAHT2_2303 protein of unknown function DUF152; PFAM: protein of unknown function DUF152; SPTR: Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family. (276 aa)    
Predicted Functional Partners:
ADW16506.1
COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904: IPR000836; KEGG: tmt:Tmath_2015 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase.
  
 
  0.919
ADW17065.1
Inosine guanosine and xanthosine phosphorylase family; COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845: IPR011268; KEGG: dak:DaAHT2_0643 purine nucleoside phosphorylase I, inosine and guanosine-specific; PFAM: purine or other phosphorylase family 1; SPTR: Inosine guanosine and xanthosine phosphorylase:Purine nucleoside phosphorylase I, inosine and guanosine-specific; TIGRFAM: inosine guanosine and xanthosine phosphorylase family; PFAM: Phosphorylase superfamily; TIGRFAM: inosine guanosine and xanthosine phosphorylase family.
    
  0.908
ADW16754.1
HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402: IPR006439: IPR005834; KEGG: dak:DaAHT2_2004 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid d [...]
    
  0.906
ADW18180.1
Conserved hypothetical protein CHP00730; COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: cja:CJA_1346 decarboxylase family protein; PFAM: Conserved hypothetical protein CHP00730; SPTR: Decarboxylase family protein; PFAM: Domain of unknown function (DUF3412); Possible lysine decarboxylase.
     
 0.904
ADW18630.1
Methylthioribose-1-phosphate isomerase; COGs: COG0182 translation initiation factor 2B subunit eIF-2B alpha/beta/delta family; InterPro IPR005251: IPR011559: IPR000649; KEGG: azl:AZL_002040 methylthioribose-1-phosphate isomerase; PFAM: initiation factor 2B related; PRIAM: S-methyl-5-thioribose-1-phosphate isomerase; SPTR: Methylthioribose-1-phosphate isomerase; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: Initiation factor 2 subunit family; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized proteins; S-meth [...]
    
  0.902
ADW16217.1
Hypothetical protein; COGs: COG0421 Spermidine synthase; KEGG: mca:MCA1034 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Spermine/spermidine synthase.
    
  0.900
ADW16495.1
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dal:Dalk_2439 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
     
  0.900
ADW17066.1
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dak:DaAHT2_0644 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
     
  0.900
ADW17280.1
COGs: COG1001 Adenine deaminase; InterPro IPR006680: IPR006679; KEGG: cpi:Cpin_1198 adenine deaminase; PFAM: amidohydrolase; PRIAM: Adenine deaminase; SPTR: Adenine deaminase; TIGRFAM: adenine deaminase; PFAM: Amidohydrolase family; TIGRFAM: adenine deaminase.
     
  0.900
ADW17354.1
5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR006179: IPR004843: IPR008334: IPR006146; KEGG: psa:PST_4140 5'-nucleotidase; PFAM: 5'-Nucleotidase domain-containing protein; metallophosphoesterase; SPTR: 5'-nucleotidase; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain.
     
  0.900
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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