Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW18907.1poly(A) polymerase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646: IPR010206; KEGG: dak:DaAHT2_1536 polynucleotide adenylyltransferase; PFAM: Polynucleotide adenylyltransferase region; SPTR: Poly(A) polymerase, PcnB; TIGRFAM: poly(A) polymerase; PFAM: Poly A polymerase head domain; TIGRFAM: poly(A) polymerase. (464 aa)    
Predicted Functional Partners:
ADW16847.1
Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646: IPR006674: IPR006675: IPR003607; KEGG: dak:DaAHT2_1316 polynucleotide adenylyltransferase/metal dependent phosphohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; Poly A polymerase head domain; TIGR [...]
  
  
 
0.922
ADW16703.1
COGs: COG0289 Dihydrodipicolinate reductase; InterPro IPR011770: IPR000846; KEGG: dak:DaAHT2_2218 dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase; PRIAM: Dihydrodipicolinate reductase; SPTR: Dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase; PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase.
 
    0.812
ADW18906.1
Endonuclease/exonuclease/phosphatase; COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: dol:Dole_2329 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/Exonuclease/phosphatase family.
 
     0.783
ADW16704.1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dps:DP0430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: Probable 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine p [...]
  
    0.768
ADW19076.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
  
  
 0.738
ADW18908.1
COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: dak:DaAHT2_1537 2-nitropropane dioxygenase NPD; PFAM: 2-nitropropane dioxygenase NPD; SPTR: 2-nitropropane dioxygenase NPD; PFAM: 2-nitropropane dioxygenase.
       0.670
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.659
ADW18154.1
COGs: COG0117 Pyrimidine deaminase; InterProIPR016192: IPR004794: IPR011549: IPR002125: IPR 002734; KEGG: dak:DaAHT2_1279 riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; CMP/dCMP deaminase zinc-binding; SPTR: Riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD.
  
    0.581
ADW18770.1
COGs: COG0594 RNase P protein component; InterPro IPR000100: IPR010916; KEGG: dps:DP0854 ribonuclease P, protein component; PFAM: ribonuclease P protein; SPTR: Ribonuclease P protein component; TIGRFAM: ribonuclease P protein component; manually curated; PFAM: Ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial.
  
  
 0.536
ADW16500.1
COGs: COG0143 Methionyl-tRNA synthetase; InterProIPR002547: IPR014758: IPR002304: IPR004495: IPR 015413; KEGG: dps:DP0786 methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); t-RNA-binding domain-containing protein; SPTR: Probable methionyl-tRNA synthetase; TIGRFAM: methionyl-tRNA synthetase; methionyl-tRNA synthetase, beta subunit; PFAM: Anticodon-binding domain; tRNA synthetases class I (M); Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase.
  
 
 0.490
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (28%) [HD]