Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW18915.1COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); InterPro IPR003699; KEGG: dak:DaAHT2_0258 S-adenosylmethionine/tRNA-ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR: Queuosine biosynthesis protein; TIGRFAM:S-adenosylmethionine/tRNA-ribosyltransferas e-isomerase; PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase. (367 aa)    
Predicted Functional Partners:
ADW16215.1
tRNA-guanine transglycosylase; COGs: COG0343 Queuine/archaeosine tRNA-ribosyltransferase; InterPro IPR004803: IPR002616; KEGG: dak:DaAHT2_1914 queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: Queuine tRNA-ribosyltransferase; TIGRFAM: queuine tRNA-ribosyltransferase; tRNA-guanine transglycosylase, various specificities; PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming.
 
 0.996
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
  
 0.825
ADW19427.1
Protein of unknown function DUF208; COGs: COG1636 conserved hypothetical protein; InterPro IPR003828; KEGG: dak:DaAHT2_1640 protein of unknown function DUF208; PFAM: protein of unknown function DUF208; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized BCR, COG1636.
 
  
 0.820
ADW17115.1
Gid protein; COGs: COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation; InterPro IPR002218: IPR004417; KEGG: dps:DP1969 tRNA (uracil-5-)-methyltransferase Gid; PFAM: glucose-inhibited division protein A; PRIAM:Methylenetetrahydrofolate--tRNA-(uracil-5-)-m ethyltransferase(FADH(2)-oxidizing); SPTR:Methylenetetrahydrofolate--tRNA-(uracil-5-)-me thyltransferasetrmFO; TIGRFAM: gid protein; PFAM: Glucose inhibited division protein A; TIGRFAM: tRNA:m(5)U-54 methyltransferase.
 
  
 0.801
ADW18897.1
KEGG: noc:Noc_0305 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2905).
  
    0.741
ADW16774.1
Sun protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR004573: IPR006027: IPR001678: IPR018314; KEGG: dak:DaAHT2_2304 sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Fmu, rRNA SAM-dependent methyltransferase; TIGRFAM: sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB.
  
    0.651
ADW18389.1
COGs: COG4786 Flagellar basal body rod protein; InterPro IPR001444: IPR010930: IPR020013; KEGG: dps:DP2680 flagellar basal-body rod protein (FlgF); PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; SPTR: Related to flagellar basal-body rod protein (FlgF); TIGRFAM: flagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; flagellar hook-basal body proteins.
    
   0.647
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
    0.611
rnc
RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.590
ADW19084.1
COGs: COG0342 Preprotein translocase subunit SecD; InterPro IPR003335: IPR005791: IPR005665; KEGG: dps:DP0806 protein-export membrane protein SecD; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: Related to protein-export membrane protein SecD; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF.
     
 0.582
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.