STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18934.1COGs: COG0162 Tyrosyl-tRNA synthetase; InterPro IPR002942: IPR002305: IPR002307: IPR001412; KEGG: dps:DP2869 tyrosyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; RNA-binding S4 domain protein; SPTR: Tyrosyl-tRNA synthetase; TIGRFAM: tyrosyl-tRNA synthetase; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase. (404 aa)    
Predicted Functional Partners:
ADW17589.1
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532: IPR002547: IPR005121: IPR005146: IPR 005147; KEGG: dps:DP1423 phenylalanyl-tRNA synthetase, beta chain; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase beta chain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bac [...]
  
  
 0.925
ADW16500.1
COGs: COG0143 Methionyl-tRNA synthetase; InterProIPR002547: IPR014758: IPR002304: IPR004495: IPR 015413; KEGG: dps:DP0786 methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); t-RNA-binding domain-containing protein; SPTR: Probable methionyl-tRNA synthetase; TIGRFAM: methionyl-tRNA synthetase; methionyl-tRNA synthetase, beta subunit; PFAM: Anticodon-binding domain; tRNA synthetases class I (M); Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase.
  
 
 0.903
ADW18092.1
COGs: COG0018 Arginyl-tRNA synthetase; InterPro IPR015945: IPR001278: IPR005148: IPR008909; KEGG: dps:DP2752 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase.
 
  
 0.891
ADW18535.1
COGs: COG0060 Isoleucyl-tRNA synthetase; InterProIPR015905: IPR002300: IPR013155: IPR010663: IPR 001412: IPR002301; KEGG: dps:DP2552 isoleucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: Isoleucyl-tRNA synthetase; TIGRFAM: isoleucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Zinc finger found in FPG and IleRS; TIGRFAM: isoleucyl-tRNA synthetase.
  
  
 0.843
prfA
Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
  
 0.835
ADW18935.1
Metal dependent phosphohydrolase; COGs: COG1418 HD superfamily hydrolase; InterProIPR004088: IPR018111: IPR006674: IPR017705: IPR 004087: IPR003607: IPR006675; KEGG: dps:DP2870 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; K Homology, type 1, subgroup; SMART: metal-dependent phosphohydrolase HD region; KH domain protein; SPTR: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; TIGRFAM: YmdA/YtgF protein; metal dependent phophohydrolase; PFAM: KH domain; HD domain; Domain of unknown function (DUF3552); TIGRFAM: conserved hypothetical protein YmdA/YtgF; uncharact [...]
       0.812
tsf
Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
  
 
 0.791
pheS
COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR004529: IPR006195: IPR004188: IPR002319; KEGG: dps:DP1424 phenylalanyl-tRNA synthetase, alpha chain; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; SPTR: Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tR [...]
  
  
 0.776
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
  
  
 0.669
ADW17000.1
COGs: COG0442 Prolyl-tRNA synthetase; InterProIPR002314: IPR007214: IPR004154: IPR002316: IPR 004500: IPR006195; KEGG: dps:DP1164 prolyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); YbaK/prolyl-tRNA synthetase associated region; Anticodon-binding domain protein; SPTR: Prolyl-tRNA synthetase; TIGRFAM: prolyl-tRNA synthetase; PFAM: YbaK / prolyl-tRNA synthetases associated domain; Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family II.
  
  
 0.660
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (28%) [HD]