Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW18940.1Molybdopterin biosynthesis MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: dps:DP2875 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Similar to molybdenum cofactor biosynthesis protein; PFAM: MoaE protein. (120 aa)    
Predicted Functional Partners:
ADW18239.1
thiamineS protein; InterPro IPR003749; KEGG: dps:DP2477 molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; SPTR: Similar to molybdopterin converting factor, subunit 1; PFAM: ThiS family.
  
 
 0.988
ADW18121.1
GTP cyclohydrolase subunit MoaC; COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: dps:DP1483 molybdenum cofactor biosynthesis protein C (MoaC); PFAM: molybdopterin cofactor biosynthesis protein MoaC; SPTR: Probable molybdenum cofactor biosynthesis protein C (MoaC); TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.
  
  
 0.938
ADW18075.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594; KEGG: cth:Cthe_0600 thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: Thiamine biosynthesis protein ThiF; PFAM: ThiF family; TIGRFAM: thiamine biosynthesis protein ThiF, family 2.
  
 0.886
ADW18242.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR006140: IPR000594; KEGG: gur:Gura_1193 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family.
  
 0.886
ADW17509.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037: IPR013099: IPR003091; KEGG: dvm:DvMF_1148 TrkA-N domain protein; PFAM: TrkA-N domain protein; Ion transport 2 domain protein; TrkA-C domain protein; SPTR: TrkA-N domain protein; PFAM: TrkA-N domain; Ion channel; TrkA-C domain.
  
    0.832
ADW17679.1
COGs: COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; InterPro IPR004435; KEGG: dps:DP1766 molybdopterin-guanine dinucleotide biosynthesis protein B; SPTR: Related to molybdopterin-guanine dinucleotide biosynthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB.
  
 
 0.818
ADW18463.1
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453: IPR008284: IPR020817; KEGG: dak:DaAHT2_1080 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
  
  
 0.778
ADW17864.1
Kef-type potassium/proton antiporter, CPA2 family; COGs: COG4651 Kef-type K+ transport system predicted NAD-binding component; InterPro IPR006153: IPR003148: IPR006037; KEGG: dps:DP1776 potassium efflux transporter; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; SPTR: Related to potassium efflux transporter; PFAM: TrkA-N domain; TrkA-C domain; Sodium/hydrogen exchanger family; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family; TC 2.A.37.1.
  
    0.689
ADW17455.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037: IPR013099: IPR020592; KEGG: glo:Glov_0875 TrkA-N domain protein; PFAM: TrkA-N domain protein; Ion transport 2 domain protein; TrkA-C domain protein; SPTR: Potassium uptake protein, TrkA family; PFAM: TrkA-N domain; Ion channel; TrkA-C domain.
   
    0.683
ADW17698.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037; KEGG: dap:Dacet_1284 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: TrkA-N domain protein; PFAM: TrkA-N domain; TrkA-C domain.
   
    0.683
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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