Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW18956.1Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR003439: IPR017940: IPR011917: IPR001140: IPR 017871: IPR003593; KEGG: dps:DP2634 ABC transporter ATP-binding protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: Lipid A export ATP-binding/permease protein MsbA; TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter; ABC transporter transmembrane region; TIGRFAM: lipid A export perme [...] (581 aa)    
Predicted Functional Partners:
ADW17736.1
COGs: COG1663 Tetraacyldisaccharide-1-P 4'-kinase; InterPro IPR003758; KEGG: dak:DaAHT2_1077 tetraacyldisaccharide 4'-kinase; PFAM: Tetraacyldisaccharide-1-P 4'-kinase; PRIAM: Tetraacyldisaccharide 4'-kinase; SPTR: Tetraacyldisaccharide 4'-kinase; TIGRFAM: tetraacyldisaccharide 4'-kinase; PFAM: Tetraacyldisaccharide-1-P 4'-kinase; TIGRFAM: tetraacyldisaccharide 4'-kinase.
  
 0.934
ADW18043.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterProIPR020845: IPR009081: IPR006163: IPR000873: IPR 002123; KEGG: ppr:PBPRB0014 acyltransferase family protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: Hypothetical acyltransferase family protein; PFAM: Phosphopantetheine attachment site; Acyltransferase; AMP-binding enzyme; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
  
 
 0.828
ADW18955.1
COGs: COG3307 Lipid A core - O-antigen ligase; InterPro IPR007016; KEGG: cpb:Cphamn1_0392 O-antigen polymerase; PFAM: O-antigen polymerase; SPTR: O-antigen polymerase; PFAM: O-Antigen ligase.
     
 0.807
ADW16692.1
ABC transporter related protein; COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: dps:DP0441 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Probable ABC transporter, ATP-binding protein; PFAM: ABC transporter.
   
0.756
ADW19398.1
AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959: IPR003593; KEGG: aeh:Mlg_1753 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; PFAM: ATPase family associated with various cellular activities (AAA).
   
 0.744
ADW18954.1
COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: nde:NIDE3030 putative lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; SPTR: ADP-heptose:LPS heptosyl transferase I; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase I; lipopolysaccharide heptosyltransferase III, putative.
 
   
 0.739
ADW17729.1
lipid-A-disaccharide synthase; COGs: COG0763 Lipid A disaccharide synthetase; InterPro IPR003835; KEGG: dak:DaAHT2_0811 lipid-A-disaccharide synthase; PFAM: glycosyl transferase family 19; PRIAM: Lipid-A-disaccharide synthase; SPTR: Lipid-A-disaccharide synthase; TIGRFAM: lipid-A-disaccharide synthase; PFAM: Lipid-A-disaccharide synthetase; TIGRFAM: lipid-A-disaccharide synthase.
 
   
 0.697
ADW17100.1
Peptidylprolyl isomerase; COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130: IPR001179: IPR020892; KEGG: dps:DP1645 peptidyl-prolyl cis-trans isomerase; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; peptidylprolyl isomerase FKBP-type; PRIAM: Peptidylprolyl isomerase; SPTR: Probable peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD.
 
 
 0.687
ADW16609.1
FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterProIPR000253: IPR003439: IPR013525: IPR017871: IPR 003593; KEGG: cag:Cagg_0751 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; PFAM: ABC transporter related; Forkhead-associated protein; ABC-2 type transporter; SMART: Forkhead-associated protein; AAA ATPase; SPTR: FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; PFAM: ABC transporter; FHA domain; ABC-2 type transporter.
  
 0.665
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.665
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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