STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADW18958.1Histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR005467: IPR003594; KEGG: dak:DaAHT2_0503 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (488 aa)    
Predicted Functional Partners:
ADW18442.1
Transcriptional regulator, XRE family; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR001387: IPR013096; KEGG: sfu:Sfum_4068 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; PFAM: Cupin domain; Helix-turn-helix.
   
 
 0.892
ADW17242.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 003594: IPR013656; KEGG: dak:DaAHT2_2397 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protei [...]
 
 
 0.859
ADW17352.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 003661: IPR003594: IPR013767; KEGG: dak:DaAHT2_1107 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Response regulator receiver; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90 [...]
 
 
 0.855
ADW16492.1
KEGG: dak:DaAHT2_2292 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 
 0.845
ADW16898.1
Adenylate/guanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR001054: IPR018297; KEGG: bja:blr2288 two-component hybrid sensor and regulator; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SPTR: Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain.
 
 
 0.810
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
 
 
 0.658
ADW19026.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR003660: IPR003661: IPR 003594: IPR004358; KEGG: gbm:Gbem_3181 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SPTR: Hpt sensor hybrid histidine kinase; [...]
 
 
 0.646
ADW18650.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR003660: IPR000014: IPR001610: IPR 003661: IPR003594: IPR001789: IPR005467: IPR000700: IPR008207:I PR013655; KEGG: dba:Dbac_2628 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain contai [...]
 
 
 0.637
ADW17465.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014: IPR005467: IPR001789: IPR000700: IPR 013656: IPR003594: IPR004358; KEGG: dma:DMR_27290 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATP [...]
 
 
 0.634
ADW18959.1
COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: dak:DaAHT2_0502 uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain.
  
    0.618
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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