Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW18973.1COGs: COG0851 Septum formation topological specificity factor; InterPro IPR005527; KEGG: maq:Maqu_2337 cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; SPTR: Cell division topological specificity factor; TIGRFAM: cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; TIGRFAM: cell division topological specificity factor MinE. (86 aa)    
Predicted Functional Partners:
ADW18974.1
Septum site-determining protein MinD; COGs: COG2894 Septum formation inhibitor-activating ATPase; InterPro IPR010223; KEGG: pag:PLES_18231 cell division inhibitor MinD; SPTR: Cell division inhibitor MinD; TIGRFAM: septum site-determining protein MinD; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD.
 
 
 0.998
ADW18975.1
Septum site-determining protein MinC; COGs: COG0850 Septum formation inhibitor; InterPro IPR005526: IPR013033; KEGG: sat:SYN_02704 cell division inhibitor; PFAM: Septum formation inhibitor MinC; SPTR: Cell division inhibitor; TIGRFAM: septum site-determining protein MinC; PFAM: Septum formation inhibitor MinC, C-terminal domain; Septum formation inhibitor MinC, N-terminal domain; TIGRFAM: septum site-determining protein MinC.
 
  
 0.936
ADW16344.1
Peptidase S26, conserved region; COGs: COG4959 Type IV secretory pathway protease TraF; InterPro IPR019533; KEGG: ppd:Ppro_0246 type IV secretory protease; PFAM: Peptidase S26, conserved region; SPTR: Type IV secretory protease; PFAM: Peptidase S26; TIGRFAM: conjugative transfer signal peptidase TraF.
   
    0.805
ADW19322.1
Domain of unknown function DUF1731; COGs: COG1090 nucleoside-diphosphate sugar epimerase; InterPro IPR001509: IPR013549: IPR010099; KEGG: dol:Dole_1467 NAD-dependent epimerase/dehydratase; PFAM: domain of unknown function DUF1731; NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: conserved hypothetical protein TIGR01777.
   
  
 0.767
ADW19323.1
Domain of unknown function DUF1731; COGs: COG1090 nucleoside-diphosphate sugar epimerase; InterPro IPR005031: IPR001509: IPR013549: IPR010099; KEGG: dps:DP1255 hypothetical protein; PFAM: domain of unknown function DUF1731; NAD-dependent epimerase/dehydratase; cyclase/dehydrase; SPTR: Putative uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase family; Polyketide cyclase / dehydrase and lipid transport; Domain of unknown function (DUF1731); TIGRFAM: conserved hypothetical protein TIGR01777.
   
  
 0.767
ADW18280.1
Signal peptidase I; InterPro IPR000223: IPR019759; KEGG: dol:Dole_0321 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type.
   
    0.751
ADW19285.1
COGs: COG0681 Signal peptidase I; InterPro IPR019759: IPR000223: IPR019756: IPR019757; KEGG: dps:DP0107 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Related to signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type.
   
    0.751
ADW19464.1
COGs: COG0704 Phosphate uptake regulator; InterPro IPR008170; KEGG: dat:HRM2_02440 PhoU2; PFAM: PhoU family protein; SPTR: PhoU2; TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU domain; TIGRFAM: phosphate transport system regulatory protein PhoU.
  
    0.721
tpx
Thiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
   
    0.695
ADW16691.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: dps:DP0442 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: Probable RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
   
    0.673
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.