STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18981.1COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dat:HRM2_40310 sigma-54 dependent two component transcriptional regulator (fis family protein); PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sigma-54 dependent two component transcriptional regulator (Fis family protein); PFAM: Response regulator receiver domain. (142 aa)    
Predicted Functional Partners:
ADW18984.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: dol:Dole_2334 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   0.945
ADW18982.1
KEGG: dol:Dole_2332 histidine kinase A domain-containing protein; SPTR: Histidine kinase A domain-containing protein.
 
 
   0.830
ADW18987.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR005467: IPR013656: IPR003661: IPR003594: IPR 004358; KEGG: dvm:DvMF_1222 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   0.803
ADW18483.1
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: ttu:TERTU_0232 response regulator receiver domain protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
  
 
   0.784
ADW17352.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 003661: IPR003594: IPR013767; KEGG: dak:DaAHT2_1107 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Response regulator receiver; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90 [...]
 
 
 0.778
ADW16876.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterPro IPR003661: IPR003594: IPR004358: IPR005467; KEGG: dak:DaAHT2_1474 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: ATP-binding region, ATPase-like:Histidine kinase A-like; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   0.774
ADW18983.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dsa:Desal_1134 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
    
0.771
ADW18997.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: dat:HRM2_38130 two-component sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Two-component sensory box histidine kinase/response regulator; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
   0.767
ADW18683.1
Multi-sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR004358: IPR003661: IPR003594: IPR005467: IPR 001901: IPR007890: IPR013656; KEGG: pfs:PFLU0007 putative two-component system, sensor kinase; PFAM: CHASE2 domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: CHASE domain/sensor histidine kinase; PFAM: CHASE2 domain; Histidine kinase-, DNA gyrase B-, and HSP90-like AT [...]
 
 
 0.766
ADW19002.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: sfu:Sfum_0617 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   0.765
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.