STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18985.1COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dol:Dole_2335 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. (406 aa)    
Predicted Functional Partners:
ADW18984.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: dol:Dole_2334 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   0.941
ADW18982.1
KEGG: dol:Dole_2332 histidine kinase A domain-containing protein; SPTR: Histidine kinase A domain-containing protein.
 
 
   0.940
ADW18983.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dsa:Desal_1134 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
    
0.759
ADW19002.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: sfu:Sfum_0617 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   0.759
ADW18995.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: sfu:Sfum_0617 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   0.747
ADW18997.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: dat:HRM2_38130 two-component sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Two-component sensory box histidine kinase/response regulator; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
 
   0.726
ADW18981.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dat:HRM2_40310 sigma-54 dependent two component transcriptional regulator (fis family protein); PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sigma-54 dependent two component transcriptional regulator (Fis family protein); PFAM: Response regulator receiver domain.
 
    
0.703
ADW16688.1
KEGG: dps:DP0753 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.691
ADW18606.1
COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR020053: IPR000771; KEGG: dal:Dalk_5159 ketose-bisphosphate aldolase class-II; PFAM: ketose-bisphosphate aldolase class-II; SPTR: Ketose-bisphosphate aldolase class-II; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases.
  
     0.684
ADW16885.1
COGs: COG0659 Sulfate permease and related transporter (MFS superfamily); InterPro IPR011547: IPR002645: IPR001902; KEGG: dps:DP0849 high affinity sulfate transporter (SulP); PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Probable high affinity sulfate transporter (SulP); TIGRFAM: sulfate transporter; PFAM: Sulfate transporter family; STAS domain; TIGRFAM: anti-anti-sigma factor; high affinity sulphate transporter 1.
     0.679
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.