Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADW18987.1COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR005467: IPR013656: IPR003661: IPR003594: IPR 004358; KEGG: dvm:DvMF_1222 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (408 aa)    
Predicted Functional Partners:
ADW18986.1
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078: IPR001789: IPR002197: IPR003593; KEGG: azl:AZL_e02970 two-component response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Two-component response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interactio [...]
 
 
   0.842
ADW18981.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dat:HRM2_40310 sigma-54 dependent two component transcriptional regulator (fis family protein); PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sigma-54 dependent two component transcriptional regulator (Fis family protein); PFAM: Response regulator receiver domain.
 
   0.797
ADW17006.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dal:Dalk_1498 histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Histidine kinase; PFAM: Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
  
 
 0.742
ADW19008.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dol:Dole_1350 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
   0.742
ADW19004.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dol:Dole_1357 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
  
   0.735
ADW16671.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: tye:THEYE_A0734 FrgC; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: FrgC; PFAM: Response regulator receiver domain.
  
   0.728
ADW17323.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: tye:THEYE_A0734 FrgC; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: FrgC; PFAM: Response regulator receiver domain.
  
   0.728
ADW18983.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dsa:Desal_1134 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
   0.712
ADW19127.1
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR000160: IPR018228; KEGG: cyh:Cyan8802_1169 response regulator receiver modulated diguanylate cyclase; PFAM: response regulator receiver; GGDEF domain containing protein; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: Response regulator receiver modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
     0.692
ADW18996.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sfu:Sfum_0618 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
  
   0.670
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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