close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19004.1COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dol:Dole_1357 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. (142 aa)    
Predicted Functional Partners:
ADW19002.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: sfu:Sfum_0617 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   0.812
ADW18995.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: sfu:Sfum_0617 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   0.802
ADW18683.1
Multi-sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR004358: IPR003661: IPR003594: IPR005467: IPR 001901: IPR007890: IPR013656; KEGG: pfs:PFLU0007 putative two-component system, sensor kinase; PFAM: CHASE2 domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: CHASE domain/sensor histidine kinase; PFAM: CHASE2 domain; Histidine kinase-, DNA gyrase B-, and HSP90-like AT [...]
 
 
 0.800
ADW18997.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: dat:HRM2_38130 two-component sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Two-component sensory box histidine kinase/response regulator; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
   0.789
ADW18484.1
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR019734: IPR001789: IPR013026; KEGG: prw:PsycPRwf_2159 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
  
 
   0.785
ADW17360.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 001610: IPR003018: IPR003661: IPR003594: IPR013767: IPR013656:I PR013655; KEGG: ppd:Ppro_3572 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS doma [...]
 
 
 0.781
ADW17352.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 003661: IPR003594: IPR013767; KEGG: dak:DaAHT2_1107 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Response regulator receiver; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90 [...]
 
 
 0.775
ADW17370.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR003660: IPR003661: IPR 003594; KEGG: dat:HRM2_10420 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
   0.773
ADW17241.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sat:SYN_00173 response regulator receiver domain-containing protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver domain; PFAM: Response regulator receiver domain.
 
     0.767
ADW18984.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: dol:Dole_2334 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
   0.761
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.