STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19027.1Histidine triad (HIT) protein; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310: IPR019808; KEGG: dak:DaAHT2_1965 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein; PFAM: HIT domain. (113 aa)    
Predicted Functional Partners:
glnA
COGs: COG0174 Glutamine synthetase; InterPro IPR004809: IPR008147: IPR008146; KEGG: dat:HRM2_45740 GlnA2; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; PRIAM: Glutamate--ammonia ligase; SPTR: Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
   
   0.742
ADW18327.1
COGs: COG1189 rRNA methylase; InterPro IPR002942: IPR002877: IPR004538; KEGG: dak:DaAHT2_0442 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: Hemolysin A; TIGRFAM: hemolysin A; manually curated; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein.
      0.702
ADW19028.1
KEGG: dps:DP0076 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.671
ADW19029.1
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014021: IPR001650: IPR006935: IPR014001; KEGG: dak:DaAHT2_0092 type III restriction protein res subunit; PFAM: type III restriction protein res subunit; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Type III restriction protein res subunit; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit.
  
 
  0.662
ADW17092.1
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR004365: IPR004364: IPR002313: IPR018149: IPR 006195; KEGG: dps:DP1629 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial.
   
 0.507
ADW18107.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: acp:A2cp1_4171 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Silent information regulator protein Sir2; PFAM: Sir2 family.
    
  0.443
ADW19327.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: dak:DaAHT2_0111 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Silent information regulator protein Sir2; PFAM: Sir2 family.
    
  0.443
ADW17306.1
Protein of unknown function DUF343; InterPro IPR005651: IPR013216; KEGG: sat:SYN_01673 putative cytoplasmic protein; PFAM: protein of unknown function DUF343; Methyltransferase type 11; SPTR: Hypothetical cytosolic protein; PFAM: Methyltransferase domain; Trm112p-like protein.
  
   0.434
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
  0.415
ADW17012.1
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: dps:DP2362 hypothetical protein; PFAM: histone deacetylase superfamily; SPTR: Putative uncharacterized protein; PFAM: Histone deacetylase domain.
    
  0.409
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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