Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
typAGTP-binding protein TypA; COGs: COG1217 membrane GTPase involved in stress response; InterProIPR000795: IPR004161: IPR000640: IPR005225: IPR 006298; KEGG: dps:DP0074 GTP-binding protein TypA/BipA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: Probable GTP-binding protein TypA/BipA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small G [...] (599 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.827
rpsI
COGs: COG0103 Ribosomal protein S9; InterPro IPR000754: IPR020574; KEGG: dps:DP1326 30S ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family.
  
    0.750
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
  
 0.739
rpmI
LSU ribosomal protein L35P; InterPro IPR001706: IPR021137: IPR018265; KEGG: dps:DP1426 50S ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: ribosomal protein L35; PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
  
    0.727
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
    0.713
ADW18183.1
Trigger factor; COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR005215: IPR008881: IPR001179: IPR008880; KEGG: dak:DaAHT2_1304 trigger factor; PFAM: trigger factor domain-containing protein; peptidylprolyl isomerase FKBP-type; SPTR: Trigger factor; TIGRFAM: trigger factor; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Bacterial trigger factor protein (TF); Bacterial trigger factor protein (TF) C-terminus; TIGRFAM: trigger factor.
  
  
 0.694
ADW19031.1
Hypothetical protein.
       0.693
ADW16496.1
GTP-binding protein YchF; COGs: COG0012 GTPase probable translation factor; InterPro IPR004396: IPR006073: IPR002917: IPR013029; KEGG: dps:DP0782 GTP-dependent nucleic acid-binding protein EngD; PFAM: protein of unknown function DUF933; GTP-binding protein HSR1-related; SPTR: Probable GTP-binding protein (YchF); TIGRFAM: GTP-binding protein YchF; PFAM: GTPase of unknown function; Protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF.
  
  
 0.609
ADW19045.1
Protein of unknown function DUF150; InterPro IPR003728: IPR020790; KEGG: dps:DP2615 hypothetical protein; PFAM: protein of unknown function DUF150; SPTR: Ribosome maturation factor rimP; PFAM: Uncharacterised BCR, YhbC family COG0779.
  
  
 0.600
ADW19022.1
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: cja:CJA_3147 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
   
  
 0.599
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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