STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19068.1COGs: COG0358 DNA primase; InterProIPR002694: IPR013264: IPR006171: IPR019475: IPR 006154: IPR006295; KEGG: dak:DaAHT2_2321 DNA primase; PFAM: DNA primase catalytic core domain; TOPRIM domain-containing protein; DNA primase, DnaB-helicase binding domain; SMART: Toprim sub domain-containing protein; SPTR: DNA primase; TIGRFAM: DNA primase; PFAM: Toprim domain; DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; DnaB-helicase binding domain of primase; TIGRFAM: DNA primase, catalytic core. (596 aa)    
Predicted Functional Partners:
ADW19069.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 0.954
ADW17980.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
 
 
 0.944
ADW17951.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284: IPR007127: IPR009042: IPR007627: IPR 007624: IPR007630: IPR000943; KEGG: dps:DP2503 RNA polymerase sigma factor (RpoD); PFAM: sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 factor, region 1.1; Sigma-70 region 3; Sigma- [...]
  
 0.918
ADW16398.1
P4 alpha zinc-binding domain protein; COGs: COG0358 DNA primase; InterPro IPR013237; KEGG: dps:DP1572 hypothetical protein; PFAM: P4 alpha zinc-binding domain protein; SPTR: Putative uncharacterized protein; PFAM: CHC2 zinc finger.
     
  0.900
ADW17116.1
Hypothetical protein; COGs: COG0305 Replicative DNA helicase; InterPro IPR007694; KEGG: ade:Adeh_1793 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: DnaB-like helicase C terminal domain.
  
 
 0.883
ADW17003.1
RNAse PH; COGs: COG0689 RNase PH; InterPro IPR001247: IPR015847: IPR002381: IPR018336; KEGG: dps:DP1273 ribonuclease PH; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2; PRIAM: tRNA nucleotidyltransferase; SPTR: Ribonuclease PH; TIGRFAM: ribonuclease PH; PFAM: 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; TIGRFAM: ribonuclease PH.
    
 
 0.869
ADW17202.1
Ribosome-associated GTPase EngA; COGs: COG1160 GTPase; InterPro IPR006073: IPR016484: IPR002917: IPR005225; KEGG: dps:DP2939 GTP-binding protein (EngA); PFAM: GTP-binding protein HSR1-related; SPTR: GTP-binding protein engA; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein domain.
   
  
 0.839
ADW17755.1
Iron-only hydrogenase maturation protein HydF; COGs: COG1160 GTPase; InterPro IPR005225: IPR002917; KEGG: sfu:Sfum_1843 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.
   
  
 0.835
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
  
   0.782
ADW17962.1
COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284: IPR007627: IPR007630: IPR000943: IPR 016263; KEGG: dps:DP2192 RNA polymerase sigma-B factor; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; alternative sigma factor RpoH.
  
 0.748
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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