Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADW19070.1DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: dak:DaAHT2_2319 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: SMF protein; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA. (376 aa)    
Predicted Functional Partners:
ADW16749.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: dak:DaAHT2_2000 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
 
 
 0.948
ADW18470.1
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477: IPR004797; KEGG: dps:DP1704 ComE operon protein 3; PFAM: ComEC/Rec2-related protein; SPTR: Related to ComE operon protein 3; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
 
  
 0.935
ADW17528.1
Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482: IPR001208: IPR000523: IPR003593; KEGG: dak:DaAHT2_1394 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: Putative enzyme (N-terminal); transcriptional regulator with P-loop containing NTP hydrolase domain (C-terminal)(YifB); TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein.
 
 0.931
ADW16478.1
COGs: COG1989 Type II secretory pathway prepilin signal peptidase PulO and related peptidase; InterPro IPR014032: IPR010627: IPR000045; KEGG: dps:DP3017 type IV prepilin leader peptidase; PFAM: peptidase A24A domain protein; peptidase A24A prepilin type IV; PRIAM: Prepilin peptidase; SPTR: Related to type IV prepilin leader peptidase; PFAM: Bacterial Peptidase A24 N-terminal domain; Type IV leader peptidase family.
  
  
 0.873
ADW19069.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
 0.816
ADW17704.1
COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: dma:DMR_08520 alkaline phosphatase precursor; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase.
  
    0.720
ADW18524.1
Uncharacterized protein family UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: dak:DaAHT2_1166 protein of unknown function UPF0102; PFAM: Uncharacterised protein family UPF0102; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: conserved hypothetical protein TIGR00252.
 
  
 0.705
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006132: IPR006131: IPR006130; KEGG: dak:DaAHT2_2315 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carb [...]
      0.679
ADW19071.1
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: dps:DP0795 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Probable ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
       0.645
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.592
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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