STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19119.1COGs: COG2021 Homoserine acetyltransferase; InterPro IPR000073: IPR008220: IPR006296; KEGG: dol:Dole_0752 homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; PRIAM: Homoserine O-acetyltransferase; SPTR: Homoserine O-acetyltransferase; TIGRFAM: homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; TIGRFAM: homoserine O-acetyltransferase. (378 aa)    
Predicted Functional Partners:
ADW19120.1
InterPro IPR010743; KEGG: dak:DaAHT2_1397 methionine biosynthesis protein MetW; PFAM: Methionine biosynthesis MetW protein; SPTR: Methionine biosynthesis MetW; TIGRFAM: methionine biosynthesis protein MetW; PFAM: Methionine biosynthesis protein MetW; TIGRFAM: methionine biosynthesis protein MetW.
  
 0.998
ADW18862.1
COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277: IPR006235; KEGG: rrs:RoseRS_1758 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
 
 0.995
ADW18707.1
COGs: COG0460 Homoserine dehydrogenase; InterProIPR016204: IPR019811: IPR005106: IPR001342: IPR 002912; KEGG: dak:DaAHT2_0885 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain.
 
 
 0.975
ADW17925.1
COGs: COG0527 Aspartokinase; InterProIPR005260: IPR001341: IPR001048: IPR002912: IPR 018042; KEGG: dak:DaAHT2_0808 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
    
 0.877
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.837
ADW19122.1
COGs: COG0031 Cysteine synthase; InterPro IPR001926: IPR005856: IPR005859; KEGG: bth:BT_3080 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases.
     
 0.831
ADW19121.1
COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: sfu:Sfum_2682 serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase.
     
 0.827
ADW18487.1
COGs: COG0133 Tryptophan synthase beta chain; InterPro IPR001926: IPR006653: IPR006654; KEGG: dps:DP1631 tryptophan synthase subunit beta; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Probable tryptophan synthase, beta subunit; TIGRFAM: tryptophan synthase, beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase, beta subunit.
     
 0.808
ADW18486.1
COGs: COG0159 Tryptophan synthase alpha chain; InterPro IPR002028: IPR018204; KEGG: dak:DaAHT2_1366 tryptophan synthase, alpha subunit; PFAM: tryptophan synthase alpha chain; SPTR: Tryptophan synthase, alpha subunit; TIGRFAM: tryptophan synthase, alpha subunit; PFAM: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit.
     
  0.800
ADW18517.1
Pyridoxal-phosphate dependent TrpB-like enzyme; COGs: COG1350 alternative tryptophan synthase beta-subunit (paralog of TrpB); InterPro IPR001926: IPR006653: IPR006316; KEGG: dak:DaAHT2_0908 pyridoxal-phosphate dependent TrpB-like enzyme; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Tryptophan synthase; SPTR: Pyridoxal-phosphate dependent TrpB-like enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme.
     
  0.800
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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