Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW19129.1COGs: COG0418 Dihydroorotase; InterPro IPR004721: IPR002195; KEGG: chl:Chy400_2972 dihydroorotase; PRIAM: Dihydroorotase; SPTR: Dihydroorotase, homodimeric type; TIGRFAM: dihydroorotase, homodimeric type; PFAM: Amidohydrolase; TIGRFAM: dihydroorotase, homodimeric type. (332 aa)    
Predicted Functional Partners:
ADW16476.1
Dihydroorotate oxidase B, catalytic subunit; COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR001295: IPR012135: IPR005720; KEGG: dps:DP3015 dihydroorotate dehydrogenase, catalytic subunit; PFAM: dihydroorotate oxidase; SPTR: Probable dihydroorotate dehydrogenase, catalytic subunit; TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein.
  
 
 0.988
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006132: IPR006131: IPR006130; KEGG: dak:DaAHT2_2315 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carb [...]
   
 
 0.987
ADW19283.1
COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680: IPR004722: IPR002195; KEGG: dak:DaAHT2_2316 dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type.
    
 0.925
ADW16477.1
Oxidoreductase FAD/NAD(P)-binding domain protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterProIPR017927: IPR012165: IPR008333: IPR001433: IPR 019480; KEGG: dps:DP3016 dihydroorotate dehydrogenase, electron transfer subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Related to dihydroorotate dehydrogenase, electron transfer subunit; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur [...]
    
  0.909
ADW17102.1
COGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR001317: IPR011702: IPR006220: IPR017926: IPR 002474: IPR000991: IPR006274; KEGG: dps:DP3095 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Probable carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit.
   
  
 0.814
carB
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005483: IPR011761: IPR005481: IPR005479: IPR 005480: IPR011607: IPR006275; KEGG: dps:DP3096 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Probable carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding dom [...]
   
  
 0.756
ADW19423.1
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005481: IPR005479: IPR005480: IPR011607: IPR 005483: IPR006275: IPR011761; KEGG: sat:SYN_02589 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-l [...]
   
  
 0.756
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
       0.746
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
    0.716
ADW17958.1
COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR000115: IPR000031: IPR020562: IPR020561: IPR 020560: IPR011761: IPR020559; KEGG: dps:DP2188 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PRIAM: Phosphoribosylamine--glycine ligase., Phosphoribosylaminoimidazole carboxylase; SPTR: Probable phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/ [...]
   
  
 0.671
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.