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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
ADW19138.1Peptidase U32; COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: dps:DP0623 proteinase (collagenase) precursor; PFAM: peptidase U32; SPTR: Probable proteinase (Collagenase); PFAM: Collagenase; Peptidase family U32. (616 aa)    
Predicted Functional Partners:
ADW18215.1
NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR001949: IPR011538: IPR019554: IPR019575; KEGG: sus:Acid_5018 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd [...]
    
   0.776
ADW17752.1
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR011538: IPR019554: IPR019575: IPR017896: IPR 017900; KEGG: dma:DMR_07840 putative NAD-reducing hydrogenase subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: Putative NAD-reducing hydrogenase subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4 [...]
  
   0.770
ADW16719.1
Methyltransferase type 11; InterPro IPR013216; KEGG: mba:Mbar_A0372 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Putative uncharacterized protein; PFAM: Methyltransferase domain.
  
  
 0.741
ADW19139.1
NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086: IPR020084; KEGG: dal:Dalk_2884 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain.
       0.554
ADW16218.1
Radical SAM domain protein; COGs: COG1242 Fe-S oxidoreductase; InterPro IPR006638: IPR007197; KEGG: gvi:glr2235 hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Glr2235 protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM protein, TIGR01212 family.
 
    0.523
ADW17055.1
Male sterility domain protein; COGs: COG0702 nucleoside-diphosphate-sugar epimerase; KEGG: dak:DaAHT2_2622 male sterility domain protein; SPTR: Male sterility domain protein; PFAM: Protein of unknown function (DUF2867); NmrA-like family.
   
   0.436
ADW17040.1
NADH dehydrogenase (ubiquinone) 30 kDa subunit; COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR001268; KEGG: ote:Oter_0745 NADH dehydrogenase (ubiquinone) 30 kDa subunit; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: NADH dehydrogenase (Ubiquinone) 30 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit.
   
   0.425
ADW18011.1
COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR010218: IPR001268; KEGG: dds:Ddes_1663 NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: NADH-quinone oxidoreductase; TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C.
   
   0.425
ADW19137.1
KEGG: hch:HCH_05358 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.414
ADW17418.1
DGC domain protein; COGs: COG4273 conserved hypothetical protein; InterPro IPR014958; KEGG: dps:DP0947 hypothetical protein; PFAM: DGC domain protein; SPTR: Putative uncharacterized protein; PFAM: DGC domain.
 
    0.406
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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