STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19166.1Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994; KEGG: drm:Dred_1765 creatinase; PFAM: peptidase M24; creatinase; SPTR: Creatinase; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. (397 aa)    
Predicted Functional Partners:
ADW19165.1
KEGG: sti:Sthe_2729 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.608
ADW18854.1
Peptidase T-like protein; COGs: COG2195 Di- and tripeptidase; InterPro IPR010162: IPR002933: IPR011650; KEGG: dps:DP0258 hypothetical protein; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: peptidase T-like protein; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: peptidase T-like protein.
  
 
 0.518
ADW19167.1
COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183: IPR005730; KEGG: dba:Dbac_2319 carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Carboxynorspermidine decarboxylase; TIGRFAM: carboxynorspermidine decarboxylase; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; TIGRFAM: carboxynorspermidine decarboxylase.
  
  
 0.511
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
   
 0.511
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.478
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
 
 0.468
ADW19168.1
COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: dba:Dbac_2320 saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase; SPTR: Saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase.
       0.465
ADW17693.1
COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: dal:Dalk_4070 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Carbon-nitrogen hydrolase.
 
 
  0.455
ADW16500.1
COGs: COG0143 Methionyl-tRNA synthetase; InterProIPR002547: IPR014758: IPR002304: IPR004495: IPR 015413; KEGG: dps:DP0786 methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); t-RNA-binding domain-containing protein; SPTR: Probable methionyl-tRNA synthetase; TIGRFAM: methionyl-tRNA synthetase; methionyl-tRNA synthetase, beta subunit; PFAM: Anticodon-binding domain; tRNA synthetases class I (M); Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase.
   
 
 0.453
ADW19233.1
COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: dal:Dalk_4070 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Carbon-nitrogen hydrolase.
 
 
  0.447
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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