Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ADW19202.1IstB domain protein ATP-binding protein; COGs: COG1484 DNA replication protein; InterPro IPR013690: IPR002611: IPR003593; KEGG: psa:PST_0581 ISPsy14, transposition helper protein; PFAM: IstB domain protein ATP-binding protein; IstB ATP binding domain protein; SMART: AAA ATPase; SPTR: ISPsy14, transposition helper protein; PFAM: IstB-like ATP binding protein; IstB-like ATP binding N-terminal. (250 aa)    
Predicted Functional Partners:
ADW19203.1
Integrase catalytic region; COGs: COG4584 Transposase and inactivated derivatives; InterPro IPR001584: IPR017895; KEGG: maq:Maqu_1224 integrase catalytic subunit; PFAM: Integrase catalytic region; SPTR: Integrase, catalytic region; PFAM: Integrase core domain.
 
 0.990
ADW17116.1
Hypothetical protein; COGs: COG0305 Replicative DNA helicase; InterPro IPR007694; KEGG: ade:Adeh_1793 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: DnaB-like helicase C terminal domain.
  
 
 0.802
ADW17980.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
 
 0.802
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
     
 0.558
ADW16420.1
InterPro IPR000477; KEGG: oih:OB1804 recombinase for Bh.Int; PFAM: RNA-directed DNA polymerase (Reverse transcriptase); SPTR: Putative uncharacterized protein; PFAM: Reverse transcriptase (RNA-dependent DNA polymerase).
  
     0.465
ADW19204.1
Domain of unknown function DUF1738; COGs: COG4227 Antirestriction protein; InterPro IPR013610: IPR017113; KEGG: mes:Meso_3793 hypothetical protein; PFAM: domain of unknown function DUF1738; SPTR: Antirestriction protein; PFAM: Domain of unknown function (DUF1738).
       0.460
ADW19201.1
KEGG: gsu:GSU0073 outer membrane protein, putative; SPTR: Outer membrane protein, putative.
       0.449
ADW19205.1
COGs: COG2003 DNA repair protein; InterPro IPR001405: IPR020891; KEGG: mpt:Mpe_A1658 hypothetical protein; PFAM: DNA repair protein RadC; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc.
     
 0.418
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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