STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADW19261.1ADP-glyceromanno-heptose 6-epimerase precursor; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509: IPR011912; KEGG: pca:Pcar_0024 ADP-L-glycero-D-mannoheptose-6-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: ADP-L-glycero-D-manno-heptose-6-epimerase; TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase. (327 aa)    
Predicted Functional Partners:
ADW18926.1
rfaE bifunctional protein; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011611: IPR011913; KEGG: nde:NIDE2553 D-beta-D-heptose 7-phosphate kinase; PFAM: PfkB domain protein; SPTR: PfkB domain protein; TIGRFAM: rfaE bifunctional protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I.
 
 
 0.901
rpsS
SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.835
ADW17101.1
COGs: COG1519 3-deoxy-D-manno-octulosonic-acid transferase; InterPro IPR007507; KEGG: dal:Dalk_3702 three-deoxy-D-manno-octulosonic-acid transferase domain protein; PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; SPTR: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; PFAM: 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase).
    
 0.831
ADW18469.1
Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; COGs: COG1519 3-deoxy-D-manno-octulosonic-acid transferase; InterPro IPR007507; KEGG: dps:DP1705 3-deoxy-D-manno-octulosonic-acid transferase; PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; SPTR: Related to 3-deoxy-D-manno-octulosonic-acid transferase; PFAM: 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase).
    
 0.831
rpsC
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
  0.827
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 0.813
rpsE
SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
   
  0.807
ADW17772.1
Lipopolysaccharide heptosyltransferase II; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR011910: IPR002201; KEGG: gme:Gmet_2345 lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; SPTR: Lipopolysaccharide heptosyltransferase II; TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II.
 
  
 0.807
rpsJ
SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
  0.806
rpsM
SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
   
  0.804
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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