STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19285.1COGs: COG0681 Signal peptidase I; InterPro IPR019759: IPR000223: IPR019756: IPR019757; KEGG: dps:DP0107 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Related to signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type. (216 aa)    
Predicted Functional Partners:
ADW18280.1
Signal peptidase I; InterPro IPR000223: IPR019759; KEGG: dol:Dole_0321 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type.
  
  
 
0.923
rnc
RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
 
  
 0.820
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006132: IPR006131: IPR006130; KEGG: dak:DaAHT2_2315 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carb [...]
  
    0.795
ADW18973.1
COGs: COG0851 Septum formation topological specificity factor; InterPro IPR005527; KEGG: maq:Maqu_2337 cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; SPTR: Cell division topological specificity factor; TIGRFAM: cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; TIGRFAM: cell division topological specificity factor MinE.
   
    0.778
ADW16997.1
Site-2 protease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR008915: IPR001478: IPR004387; KEGG: dak:DaAHT2_0974 membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP.
 
  
 0.750
ADW17432.1
ATP synthase F0 subcomplex C subunit; InterPro IPR017708: IPR005953: IPR000454: IPR002379; KEGG: nhl:Nhal_1907 alternate F1F0 ATPase, F0 subunit C; PFAM: H+transporting two-sector ATPase C subunit; SPTR: Strongly similar to ATPE encoding subunit c of ATP synthase; TIGRFAM: alternate F1F0 ATPase, F0 subunit C; ATP synthase F0, C subunit; PFAM: ATP synthase subunit C; TIGRFAM: ATP synthase, F0 subunit c; alternate F1F0 ATPase, F0 subunit C.
    
 0.736
atpE
ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
    
 0.736
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.719
ADW18525.1
RNase HII; COGs: COG0164 Ribonuclease HII; InterPro IPR001352; KEGG: dps:DP2806 ribonuclease HII; PFAM: ribonuclease HII/HIII; PRIAM: Ribonuclease H; SPTR: Ribonuclease HII; PFAM: Ribonuclease HII.
  
    0.718
ADW19097.1
SSU ribosomal protein S12P methylthiotransferase; COGs: COG0621 2-methylthioadenine synthetase; InterProIPR002792: IPR013848: IPR007197: IPR005840: IPR 020612: IPR006638: IPR005839; KEGG: dak:DaAHT2_2543 MiaB-like tRNA modifying enzyme YliG; PFAM: protein of unknown function UPF0004; Radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: MiaB-like tRNA modifying enzyme YliG; RNA modification enzyme, MiaB family; PFAM: TRAM domain; Radical SAM superfamily; Uncharacterized protein family [...]
  
    0.699
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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