STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19304.1COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR004010: IPR003660: IPR010822: IPR001932; KEGG: ppd:Ppro_1527 serine phosphatase; PFAM: Stage II sporulation protein E; Cache domain protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: Serine phosphatase; PFAM: HAMP domain; Cache domain; Stage II sporulation protein E (SpoIIE). (644 aa)    
Predicted Functional Partners:
ADW19302.1
ATP-binding region ATPase domain protein; InterPro IPR003594; KEGG: ppd:Ppro_1525 putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: Putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 0.993
ADW19303.1
COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645: IPR003658; KEGG: ppd:Ppro_1526 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
 
 
 0.990
ADW19298.1
KEGG: ppd:Ppro_1522 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 0.957
ADW19305.1
NMT1/THI5 like domain protein; COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: glo:Glov_2024 NMT1/THI5 like domain protein; SPTR: NMT1/THI5 like domain protein; PFAM: NMT1/THI5 like.
 
     0.944
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
 
  
 0.920
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
 
  
 0.909
ADW19297.1
KEGG: ppd:Ppro_1521 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.893
ADW17691.1
Hemerythrin-like metal-binding protein; InterPro IPR012827: IPR012312: IPR009875; KEGG: app:CAP2UW1_0521 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: type IV pilus assembly PilZ; Hemerythrin HHE cation binding domain protein; SPTR: Ggdef domain protein protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain; PilZ domain; TIGRFAM: hemerythrin-like metal-binding domain.
  
 
 0.888
ADW17854.1
Hypothetical protein; KEGG: ppd:Ppro_1605 anti-sigma-factor antagonist domain-containing protein; SPTR: Anti-sigma-factor antagonist (STAS) domain protein.
  
 
 0.888
ADW17261.1
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR008207: IPR 003661: IPR003594; KEGG: pth:PTH_2386 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SPTR: Signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [...]
  
 0.883
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.