Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW19319.1PAS modulated sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR013656: IPR002078: IPR002197: IPR020441: IPR 000014: IPR003593; KEGG: dde:Dde_0318 Fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold-4 domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: Putative transcriptional regulator, Fis family; TIGRFAM: PAS sensor protein; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; [...] (472 aa)    
Predicted Functional Partners:
ADW16691.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: dps:DP0442 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: Probable RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.809
ADW19318.1
KEGG: sfu:Sfum_3134 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.603
ADW19320.1
Hypothetical protein; KEGG: dat:HRM2_05880 signal transduction family protein (GGDEF domain protein); SPTR: Signal transduction family protein (GGDEF domain protein).
       0.440
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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