STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19328.1DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR005580: IPR014021: IPR 014014: IPR000629: IPR014001; KEGG: dps:DP1690 ATP-dependent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DbpA RNA-binding domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Probable ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase. (552 aa)    
Predicted Functional Partners:
ADW17100.1
Peptidylprolyl isomerase; COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130: IPR001179: IPR020892; KEGG: dps:DP1645 peptidyl-prolyl cis-trans isomerase; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; peptidylprolyl isomerase FKBP-type; PRIAM: Peptidylprolyl isomerase; SPTR: Probable peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD.
 
 0.987
ADW17264.1
Carbohydrate kinase, YjeF related protein; COGs: COG0063 sugar kinase; InterPro IPR000631: IPR004443: IPR017953; KEGG: dak:DaAHT2_0242 carbohydrate kinase, YjeF related protein; PFAM: YjeF-family domain-containing protein; protein of unknown function UPF0031; SPTR: Carbohydrate kinase, YjeF related protein; TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; Carbohydrate kinase; TIGRFAM: yjeF N-terminal region; yjeF C-terminal region, hydroxyethylthiazole kinase-related.
  
 0.969
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
 
 0.955
ADW16966.1
COGs: COG0088 Ribosomal protein L4; InterPro IPR002136; KEGG: dak:DaAHT2_1451 ribosomal protein L4/L1e; PFAM: ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4; PFAM: Ribosomal protein L4/L1 family.
   
 0.922
rplC
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.914
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
   
 0.911
ADW16962.1
COGs: COG0480 Translation elongation factors (GTPase); InterProIPR000795: IPR004161: IPR005517: IPR000640: IPR 004540: IPR005225; KEGG: dps:DP1121 translation elongation factor EF-G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein; SPTR: Elongation factor G 2; TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: [...]
   
 0.911
fusA-2
COGs: COG0480 Translation elongation factors (GTPase); InterProIPR000795: IPR004161: IPR005517: IPR000640: IPR 004540: IPR005225; KEGG: dps:DP2398 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein; SPTR: Probable elongation factor G; TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: transla [...]
   
 0.911
ADW17740.1
ATP-dependent helicase HrpB; COGs: COG1643 HrpA-like helicase; InterProIPR010225: IPR014001: IPR001650: IPR011545: IPR 007502: IPR013689: IPR014021; KEGG: dak:DaAHT2_0986 ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; ATP-dependent helicase C-terminal; Helicase associated domain (HA2); DEAD/DEAH [...]
   
 0.905
ADW17761.1
COGs: COG1643 HrpA-like helicase; InterProIPR010222: IPR014001: IPR003593: IPR001650: IPR 007502: IPR011709: IPR014021; KEGG: dak:DaAHT2_0729 ATP-dependent helicase HrpA; PFAM: helicase-associated domain protein; helicase domain protein; protein of unknown function DUF1605; SMART: DEAD-like helicase; AAA ATPase; helicase domain protein; SPTR: ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); Domain of unknown function (DUF3418); Domain of unknown function (DUF1605); DEAD/DEAH box helicase; TI [...]
   
 0.905
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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