STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19331.1COGs: COG0650 Formate hydrogenlyase subunit 4; KEGG: dps:DP1046 hydrogenase, component C-formate hydrogenlyase subunit 4; SPTR: Related to hydrogenase, component C-formate hydrogenlyase subunit 4; PFAM: NADH dehydrogenase. (304 aa)    
Predicted Functional Partners:
ADW19335.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: dps:DP1042 hydrogenase, component I-formate hydrogenlyase subunit 7; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: Related to hydrogenase, component I-formate hydrogenlyase subunit 7; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.999
ADW19334.1
COGs: COG3261 Ni Fe-hydrogenase III large subunit; KEGG: dps:DP1043 hydrogenase, component E-formate hydrogenlyase subunit 5; SPTR: Related to hydrogenase, component E-formate hydrogenlyase subunit 5; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit.
 
 
 0.997
ADW19333.1
NADH/Ubiquinone/plastoquinone (complex I); COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750: IPR003918; KEGG: dps:DP1044 hydrogenase, component F-formate hydrogenlyase subunit 3; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Probable hydrogenase, component F-formate hydrogenlyase subunit 3; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains.
 
 
 0.994
ADW19330.1
NADH/Ubiquinone/plastoquinone (complex I); COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750: IPR003918; KEGG: dps:DP1047 hydrogenase, component B-formate hydrogenlyase subunit 3; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Probable hydrogenase, component B-formate hydrogenlyase subunit 3; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains.
 
 
 0.993
ADW19332.1
Hypothetical protein; COGs: COG4237 Hydrogenase 4 membrane component (E); KEGG: dps:DP1045 hypothetical protein; SPTR: Hypothetical membrane protein.
 
  
 0.980
ADW17753.1
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352: IPR001041: IPR019574: IPR004108: IPR 003149: IPR017896: IPR017900: IPR000283; KEGG: dma:DMR_07830 putative Fe hydrogenase; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Putative Fe hydrogenase; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulf [...]
  
 
 0.925
ADW17048.1
Multisubunit sodium/proton antiporter, MrpD subunit; COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750: IPR003918; KEGG: dak:DaAHT2_1920 NADH/ubiquinone/plastoquinone (complex I); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH/Ubiquinone/plastoquinone (Complex I); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TC 2.A.63.1.
 
 
 0.908
ADW18250.1
Multisubunit potassium/proton antiporter, PhaD subunit; COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR003918: IPR001750; KEGG: dba:Dbac_2486 NADH/ubiquinone/plastoquinone (complex I); PFAM: NADH/Ubiquinone/plastoquinone (complex I); PRIAM: NADH dehydrogenase (quinone); SPTR: NADH/Ubiquinone/plastoquinone (Complex I); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TC 2.A.63.1.1.
  
 
 0.889
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
  
 
 0.854
ADW18248.1
Multisubunit potassium/proton antiporter, PhaA subunit; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR003916: IPR001516: IPR001750: IPR007182; KEGG: dba:Dbac_2484 putative monovalent cation/H+ antiporter subunit A; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; Na+/H+ antiporter MnhB subunit-related protein; SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; NADH-Ubiquinone/plastoquinone [...]
  
 
 0.830
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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