STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19338.1SPFH domain, Band 7 family protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107: IPR001972; KEGG: cts:Ctha_1815 band 7 protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: Band 7 protein; PFAM: SPFH domain / Band 7 family. (311 aa)    
Predicted Functional Partners:
ADW19339.1
Protein of unknown function DUF107; COGs: COG1585 Membrane protein implicated in regulation of membrane protease activity; InterPro IPR002810; KEGG: dal:Dalk_3751 protein of unknown function DUF107; PFAM: protein of unknown function DUF107; SPTR: Putative uncharacterized protein; PFAM: NfeD-like.
 
  
 0.965
ADW16558.1
Membrane protease FtsH catalytic subunit; COGs: COG0465 ATP-dependent Zn protease; InterProIPR005936: IPR003959: IPR000642: IPR003960: IPR 003593; KEGG: mfa:Mfla_1168 FtsH-2 peptidase; PFAM: peptidase M41; AAA ATPase central domain protein; PRIAM: Microtubule-severing ATPase; SMART: AAA ATPase; SPTR: FtsH-2 peptidase. Metallo peptidase. MEROPS family M41; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH.
   
 0.912
ADW16800.1
Membrane protease FtsH catalytic subunit; COGs: COG0465 ATP-dependent Zn protease; InterProIPR003959: IPR000642: IPR005936: IPR003960: IPR 003593; KEGG: gsu:GSU1809 cell division protein FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: Cell division protein FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH.
   
 0.912
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.912
ADW18353.1
Membrane protease FtsH catalytic subunit; COGs: COG0465 ATP-dependent Zn protease; InterProIPR003593: IPR003959: IPR000642: IPR003960: IPR 005936; KEGG: dak:DaAHT2_0902 ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; PRIAM: Microtubule-severing ATPase; SMART: AAA ATPase; SPTR: ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH.
   
 0.904
ADW16916.1
COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107: IPR010201; KEGG: dps:DP1092 lambda CII stability-governing protein (HflK); PFAM: band 7 protein; SMART: band 7 protein; SPTR: Probable lambda CII stability-governing protein (HflK); TIGRFAM: HflK protein; PFAM: SPFH domain / Band 7 family; TIGRFAM: HflK protein.
  
   
 0.749
ADW18479.1
Peptidase M16 domain protein; COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765: IPR007863; KEGG: sus:Acid_7201 peptidase M16 domain-containing protein; PFAM: peptidase M16 domain protein; SPTR: Peptidase M16 domain protein; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16).
  
 0.741
ADW18637.1
Peptidase M16 domain protein; COGs: COG0612 Zn-dependent peptidase; InterPro IPR001431: IPR011765: IPR007863; KEGG: dal:Dalk_3930 peptidase M16 domain protein; PFAM: peptidase M16 domain protein; SPTR: Peptidase M16 domain protein; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16).
  
 0.741
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
 0.720
ADW19398.1
AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959: IPR003593; KEGG: aeh:Mlg_1753 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; PFAM: ATPase family associated with various cellular activities (AAA).
   
 0.699
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (24%) [HD]