STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADW19358.1SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR003395; KEGG: ppd:Ppro_2570 SMC domain-containing protein; PFAM: SMC domain protein; SPTR: SMC domain protein; TIGRFAM: exonuclease SbcC. (1220 aa)    
Predicted Functional Partners:
ADW19357.1
COGs: COG0420 DNA repair exonuclease; InterPro IPR004843: IPR004593; KEGG: gur:Gura_1979 nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; SPTR: Exodeoxyribonuclease I subunit D; TIGRFAM: nuclease SbcCD, D subunit; PFAM: Calcineurin-like phosphoesterase; Type 5 capsule protein repressor C terminal; TIGRFAM: exonuclease SbcD.
 0.999
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
  
 0.985
ADW17332.1
HRDC domain protein; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR002121; KEGG: dat:HRM2_02150 helicase-family protein; PFAM: HRDC domain protein; SMART: HRDC domain protein; SPTR: Helicase-family protein; PFAM: PIF1 helicase; HRDC domain.
  
 0.965
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.888
ADW17061.1
DNA topoisomerase III; COGs: COG0550 Topoisomerase IA; InterProIPR006171: IPR013497: IPR000380: IPR005738: IPR 006154: IPR003601: IPR003602; KEGG: dps:DP2617 DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-containing protein; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain-containing protein; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase III; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacteria and conjugative plasmid.
  
 0.880
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
    
   0.769
ADW17260.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016: IPR014017: IPR004013: IPR000212; KEGG: gme:Gmet_3223 UvrD/REP helicase; PFAM: UvrD/REP helicase; PHP domain protein; SPTR: UvrD/REP helicase; PFAM: UvrD/REP helicase; TIGRFAM: conserved hypothetical protein TIGR00375.
  
 
 0.759
ADW17718.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212: IPR014016: IPR014017; KEGG: dps:DP2879 ATP-dependent DNA helicase UvrD; PFAM: UvrD/REP helicase; SPTR: Probable ATP-dependent DNA helicase, UvrD/REP family; PFAM: UvrD/REP helicase.
  
 
 0.759
ADW19356.1
Domain of unknown function DUF1737; COGs: COG5515 Uncharacterized conserved small protein; InterPro IPR013619; KEGG: azc:AZC_3737 hypothetical protein; PFAM: domain of unknown function DUF1737; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF1737).
       0.718
ADW16641.1
Helicase, RecD/TraA family; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR006345; KEGG: dat:HRM2_23450 RecD1; SPTR: RecD1; TIGRFAM: helicase, RecD/TraA family; PFAM: Viral (Superfamily 1) RNA helicase; TIGRFAM: helicase, putative, RecD/TraA family.
 
 
 
 0.701
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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