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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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ADW19365.1MiaB-like tRNA modifying enzyme; COGs: COG0621 2-methylthioadenine synthetase; InterProIPR013848: IPR007197: IPR005839: IPR006467: IPR 020612: IPR006638; KEGG: dps:DP2956 hypothetical protein; PFAM: protein of unknown function UPF0004; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family. (444 aa)    
Predicted Functional Partners:
ADW19364.1
COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR004506; KEGG: dak:DaAHT2_1911 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; SPTR: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase.
  
  
 0.852
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.755
ADW19366.1
Competence/damage-inducible protein cinA; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453: IPR008136: IPR008135; KEGG: dak:DaAHT2_1904 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain.
  
  
 0.752
ADW17921.1
23S rRNA m(2)A-2503 methyltransferase; COGs: COG0820 Fe-S-cluster redox enzyme; InterPro IPR004383: IPR006638: IPR007197; KEGG: dps:DP1935 hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Ribosomal RNA large subunit methyltransferase N; TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM enzyme, Cfr family.
 
  
 0.714
ADW16774.1
Sun protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR004573: IPR006027: IPR001678: IPR018314; KEGG: dak:DaAHT2_2304 sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Fmu, rRNA SAM-dependent methyltransferase; TIGRFAM: sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB.
  
  
 0.667
ADW16574.1
COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR004559: IPR007197: IPR010723: IPR006638; KEGG: dak:DaAHT2_1956 oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase.
 
  
 0.548
ADW19363.1
KEGG: dak:DaAHT2_1395 putative transcriptional regulator, XRE family; SPTR: Putative uncharacterized protein; PFAM: Helix-turn-helix.
       0.542
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
 
  
 0.525
ADW17928.1
COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR018022: IPR002627; KEGG: dak:DaAHT2_0798 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA delta(2)-isopentenylpyrophosphate transferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: IPP transferase; TIGRFAM: tRNA isopentenyltransferase (miaA).
  
 0.521
nifU
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
     
 0.521
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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