STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADW19407.1Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: dps:DP0725 DNA-binding transcriptional regulator IlvY; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Probable transcriptional activator protein (IlvY); PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain. (312 aa)    
Predicted Functional Partners:
ADW19406.1
COGs: COG0059 Ketol-acid reductoisomerase; InterPro IPR013116: IPR000506: IPR014359: IPR013023; KEGG: dat:HRM2_21070 ketol-acid reductoisomerase; PFAM: acetohydroxy acid isomeroreductase; Acetohydroxy acid isomeroreductase catalytic domain-containing protein; PRIAM: Ketol-acid reductoisomerase; SPTR: IlvC; TIGRFAM: ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase.
 
   
 0.808
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.760
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.724
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.721
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.685
ADW17037.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: dak:DaAHT2_2578 transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family.
  
     0.676
ADW16224.1
ABC transporter related protein; COGs: COG1119 ABC-type molybdenum transport system ATPase component/photorepair protein PhrA; InterPro IPR017871: IPR003439: IPR003593; KEGG: dat:HRM2_21060 ModF; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ModF; PFAM: ABC transporter.
  
     0.594
ADW19022.1
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: cja:CJA_3147 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.546
ADW17820.1
Aminotransferase class I and II; COGs: COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase; InterPro IPR004839; KEGG: hch:HCH_01903 valine--pyruvate transaminase; PFAM: aminotransferase class I and II; SPTR: Alanine-alpha-ketoisovalerate/valine-pyruvate aminotransferase; PFAM: Aminotransferase class I and II.
  
     0.496
ADW17962.1
COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284: IPR007627: IPR007630: IPR000943: IPR 016263; KEGG: dps:DP2192 RNA polymerase sigma-B factor; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; alternative sigma factor RpoH.
    
 
 0.455
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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