STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19428.1DNA-binding protein Fis; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR003018: IPR002078: IPR002197: IPR020441: IPR 003593; KEGG: dps:DP0709 nitrogen fixation protein (AnfA); PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: GAF domain protein; AAA ATPase; SPTR: Related to nitrogen fixation protein (AnfA); PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: Nif-specific regulatory protein. (523 aa)    
Predicted Functional Partners:
ADW16245.1
Transcriptional regulator, NifA, Fis Family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR002078: IPR020441: IPR003018: IPR003593: IPR 010113: IPR002197; KEGG: dak:DaAHT2_2454 transcriptional regulator, NifA subfamily, fis family; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: GAF domain protein; AAA ATPase; SPTR: Transcriptional regulator, NifA subfamily, Fis Family; TIGRFAM: Nif-specific regulatory protein; PFAM: GAF domain; Bacterial regulatory protein, F [...]
  
  
 
0.908
ADW19427.1
Protein of unknown function DUF208; COGs: COG1636 conserved hypothetical protein; InterPro IPR003828; KEGG: dak:DaAHT2_1640 protein of unknown function DUF208; PFAM: protein of unknown function DUF208; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized BCR, COG1636.
       0.810
ADW16691.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: dps:DP0442 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: Probable RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.792
ADW19426.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; COGs: COG0127 Xanthosine triphosphate pyrophosphatase; InterPro IPR020922: IPR002637; KEGG: dps:DP0707 nucleoside-triphosphatase; PFAM: Ham1 family protein; SPTR: Nucleoside-triphosphatase; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family.
       0.618
ADW16778.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 004358: IPR001638: IPR013767: IPR003661: IPR003594: IPR001610; KEGG: dol:Dole_3272 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; extracellular solute-binding protein family 3; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; extracellular solute-binding protein family 3; PAC r [...]
   
 
 0.616
ADW17314.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 001610: IPR003661: IPR003594: IPR011620: IPR013767; KEGG: ppd:Ppro_3150 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: PAS/PAC s [...]
   
 
 0.605
ADW17465.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014: IPR005467: IPR001789: IPR000700: IPR 013656: IPR003594: IPR004358; KEGG: dma:DMR_27290 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATP [...]
   
 
 0.605
ADW19056.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR005467: IPR000014: IPR000700: IPR013656: IPR 003661: IPR003594: IPR004358: IPR001610; KEGG: dak:DaAHT2_1107 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase- [...]
   
 
 0.605
ADW17360.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 001610: IPR003018: IPR003661: IPR003594: IPR013767: IPR013656:I PR013655; KEGG: ppd:Ppro_3572 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS doma [...]
   
 
 0.579
ADW17683.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014: IPR005467: IPR001789: IPR000700: IPR 013767: IPR003661: IPR003594: IPR001610: IPR004358; KEGG: dol:Dole_3265 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC s [...]
   
 
 0.542
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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