STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19433.1COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR004839: IPR001176: IPR001917; KEGG: dps:DP0642 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase. (372 aa)    
Predicted Functional Partners:
ADW17123.1
COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807: IPR020565; KEGG: dak:DaAHT2_0351 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase.
 
 0.999
ADW17199.1
COGs: COG0107 Imidazoleglycerol-phosphate synthase; InterProIPR017926: IPR014640: IPR000991: IPR006062: IPR 010139: IPR004651; KEGG: dak:DaAHT2_2087 imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: histidine biosynthesis protein; glutamine amidotransferase class-I; SPTR: Imidazoleglycerol phosphate synthase, cyclase subunit; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: Glutamine amidotransferase class-I; Histidine biosynthesis protein; TIGRFAM: imidazole glycerol phosphate sy [...]
 
  
 0.996
ADW17081.1
COGs: COG0141 Histidinol dehydrogenase; InterPro IPR012131: IPR001692; KEGG: dps:DP1282 histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; PRIAM: Histidinol dehydrogenase; SPTR: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase.
  
 0.994
ADW18324.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR003099: IPR002912; KEGG: dps:DP2275 P-protein; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Prephenate dehydrogenase; SPTR: Related to P-protein; PFAM: Prephenate dehydratase; Prephenate dehydrogenase; ACT domain.
  
 
 0.988
ADW17166.1
Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR002701: IPR001086: IPR008242: IPR020822: IPR 002912: IPR018528; KEGG: dps:DP2171 P-protein; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Probable P-protein; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
  
 
 0.949
ADW17966.1
COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496; KEGG: dps:DP2639 phosphoribosyl-AMP cyclohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase; PRIAM: Phosphoribosyl-AMP cyclohydrolase; SPTR: Phosphoribosyl-AMP cyclohydrolase; PFAM: Phosphoribosyl-AMP cyclohydrolase.
 
  
 0.945
ADW18697.1
COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR010140: IPR004013; KEGG: dps:DP2888 histidinol-phosphatase; PFAM: PHP domain protein; SPTR: Related to histidinol-phosphatase; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family.
 
 
 0.935
ADW19296.1
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR004839: IPR001176; KEGG: ppd:Ppro_1520 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase.
  
  
 
0.916
hisG
ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
 
  
 0.900
ADW19434.1
COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: dak:DaAHT2_2673 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
 
    0.899
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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