STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19448.13-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023: IPR006549; KEGG: dak:DaAHT2_1325 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; PRIAM: 3-deoxy-manno-octulosonate-8-phosphatase; SPTR: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphat [...] (213 aa)    
Predicted Functional Partners:
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006269: IPR006218; KEGG: dps:DP0765 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; SPTR: 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase.
  
 0.999
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
  
 0.997
ADW19078.1
KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR001347: IPR004800; KEGG: dak:DaAHT2_1635 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SMART: CBS domain containing protein; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein.
  
 0.994
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.814
ADW19449.1
Protein of unknown function DUF1239; InterPro IPR010664; KEGG: dps:DP0763 hypothetical protein; PFAM: protein of unknown function DUF1239; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1239).
       0.810
ADW19144.1
rfaE bifunctional protein; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterProIPR003010: IPR004820: IPR000560: IPR001110: IPR 011914: IPR004821; KEGG: dak:DaAHT2_1981 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; cytidylyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; TIGRFAM: rfaE bifunctional protein; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; Carbon-nitrogen hydrolase; TIGRFAM: rfaE bifunc [...]
      0.700
dapL
LL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.
  
    0.644
ADW16251.1
Na+/Ca+ antiporter, CaCA family; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004481: IPR004837; KEGG: cli:Clim_1218 Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; SPTR: K+-dependent Na+/Ca+ exchanger related-protein; TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein.
    
 0.640
ADW17729.1
lipid-A-disaccharide synthase; COGs: COG0763 Lipid A disaccharide synthetase; InterPro IPR003835; KEGG: dak:DaAHT2_0811 lipid-A-disaccharide synthase; PFAM: glycosyl transferase family 19; PRIAM: Lipid-A-disaccharide synthase; SPTR: Lipid-A-disaccharide synthase; TIGRFAM: lipid-A-disaccharide synthase; PFAM: Lipid-A-disaccharide synthetase; TIGRFAM: lipid-A-disaccharide synthase.
 
   
 0.612
ADW18469.1
Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; COGs: COG1519 3-deoxy-D-manno-octulosonic-acid transferase; InterPro IPR007507; KEGG: dps:DP1705 3-deoxy-D-manno-octulosonic-acid transferase; PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; SPTR: Related to 3-deoxy-D-manno-octulosonic-acid transferase; PFAM: 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase).
 
   
 0.605
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.