Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW19451.1COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterProIPR019546: IPR006137: IPR001821: IPR006311: IPR 017909; KEGG: mag:amb1650 Ni,Fe-hydrogenase I small subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Twin-arginine translocation pathway, signal sequence, subgroup; PRIAM: Hydrogenase (acceptor); SPTR: Ni,Fe-hydrogenase I small subunit; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; hydrogenase (NiFe) small subunit (hydA). (364 aa)    
Predicted Functional Partners:
ADW17937.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501: IPR018194; KEGG: mag:amb1114 Ni,Fe-hydrogenase I large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase.
 0.999
ADW19453.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501: IPR018194; KEGG: dar:Daro_3971 nickel-dependent hydrogenase, large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Nickel-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase.
 
 0.999
ADW17938.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR006137: IPR001821; KEGG: dal:Dalk_2280 Ni,Fe-hydrogenase I small subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: Ni,Fe-hydrogenase I small subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA).
 
  
 
0.934
ADW19454.1
COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: etr:ETAE_2363 predicted maturation element for hydrogenase 2; PFAM: peptidase M52 hydrogen uptake protein; SPTR: Hydrogenase expression/formation protein; TIGRFAM: hydrogenase maturation protease; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease.
 
  
 0.934
dsrA
COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterPro IPR017896: IPR006067: IPR011806; KEGG: dps:DP0797 dissimilatory sulfite reductase, alpha subunit (DsrA); PFAM: nitrite and sulphite reductase 4Fe-4S region; PRIAM: Hydrogensulfite reductase; SPTR: Dissimilatory sulfite reductase subunit A; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit.
   
 
  0.900
dsrB
COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterProIPR017896: IPR005117: IPR006067: IPR017900: IPR 011808; KEGG: dps:DP0798 dissimilatory sulfite reductase, beta subunit (DsrB); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; PRIAM: Hydrogensulfite reductase; SPTR: Dissimilatory sulfite reductase subunit B; TIGRFAM: sulfite reductase, dissimilatory-type beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like [...]
   
 
  0.900
ADW17901.1
Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR003495: IPR012202; KEGG: dps:DP0583 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Probable hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.
 
  
 0.866
ADW19455.1
COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: sus:Acid_4205 polysulphide reductase, NrfD; PFAM: Polysulphide reductase NrfD; SPTR: Polysulphide reductase, NrfD; PFAM: Polysulphide reductase, NrfD.
 
  
 0.798
ADW17899.1
Hydrogenase expression/formation protein HypE; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR011854: IPR000728: IPR010918; KEGG: dps:DP0580 hydrogenase accessory protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; SPTR: Probable hydrogenase accessory protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE.
 
   
 0.780
ADW19452.1
Hydrogenase 2 protein HybA; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR006311: IPR017909: IPR017896: IPR017900; KEGG: mag:amb1649 hydrogenase 2 protein HybA; SPTR: Fe-S-cluster-containing hydrogenase components 1; PFAM: TAT (twin-arginine translocation) pathway signal sequence; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
  
  
 0.735
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.