Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW19455.1COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: sus:Acid_4205 polysulphide reductase, NrfD; PFAM: Polysulphide reductase NrfD; SPTR: Polysulphide reductase, NrfD; PFAM: Polysulphide reductase, NrfD. (374 aa)    
Predicted Functional Partners:
ADW19452.1
Hydrogenase 2 protein HybA; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR006311: IPR017909: IPR017896: IPR017900; KEGG: mag:amb1649 hydrogenase 2 protein HybA; SPTR: Fe-S-cluster-containing hydrogenase components 1; PFAM: TAT (twin-arginine translocation) pathway signal sequence; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
 
 0.946
ADW18049.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017900: IPR017896: IPR014603; KEGG: drm:Dred_0462 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
 
 0.913
ADW16802.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR006311: IPR017900: IPR017909: IPR017896; KEGG: geo:Geob_1593 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
 
 0.905
ADW19453.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501: IPR018194; KEGG: dar:Daro_3971 nickel-dependent hydrogenase, large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Nickel-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase.
 
  
 0.902
ADW19454.1
COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: etr:ETAE_2363 predicted maturation element for hydrogenase 2; PFAM: peptidase M52 hydrogen uptake protein; SPTR: Hydrogenase expression/formation protein; TIGRFAM: hydrogenase maturation protease; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease.
 
  
 0.870
ADW19451.1
COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterProIPR019546: IPR006137: IPR001821: IPR006311: IPR 017909; KEGG: mag:amb1650 Ni,Fe-hydrogenase I small subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Twin-arginine translocation pathway, signal sequence, subgroup; PRIAM: Hydrogenase (acceptor); SPTR: Ni,Fe-hydrogenase I small subunit; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; hydrogenase (NiFe) small subunit (hydA).
 
  
 0.798
ADW17542.1
Periplasmic nitrate reductase subunit NapA apoprotein; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR006311: IPR017909: IPR006963: IPR006656: IPR 006657; KEGG: dap:Dacet_0086 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: periplasmic nitrate reductase, large subunit; Tat (twin-argi [...]
  
 
 0.703
tuf
Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
   0.662
ADW16963.1
COGs: COG0050 GTPase - translation elongation factors; InterProIPR000795: IPR004161: IPR004160: IPR004541: IPR 005225; KEGG: dps:DP1109 elongation factor Tu; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor Tu domain-containing protein; SPTR: Elongation factor Tu 1; TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU.
  
   0.662
ADW18007.1
Trimethylamine-N-oxide reductase (cytochrome c); COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006655: IPR006963: IPR006656: IPR006657; KEGG: dvm:DvMF_0320 formate dehydrogenase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Trimethylamine-N-oxide reductase (cytochrome c); SPTR: Formate dehydrogenase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain.
  
 
 0.640
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.