STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19460.1Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839: IPR004838; KEGG: dat:HRM2_45660 putative histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase. (364 aa)    
Predicted Functional Partners:
ADW19461.1
Adenosylcobinamide-phosphate synthase; COGs: COG1270 Cobalamin biosynthesis protein CobD/CbiB; InterPro IPR004485; KEGG: dat:HRM2_45650 CbiB; PFAM: cobalamin biosynthesis protein CbiB; SPTR: CbiB; TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: CobD/Cbib protein; TIGRFAM: cobalamin biosynthesis protein CobD.
  
 0.997
ADW17199.1
COGs: COG0107 Imidazoleglycerol-phosphate synthase; InterProIPR017926: IPR014640: IPR000991: IPR006062: IPR 010139: IPR004651; KEGG: dak:DaAHT2_2087 imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: histidine biosynthesis protein; glutamine amidotransferase class-I; SPTR: Imidazoleglycerol phosphate synthase, cyclase subunit; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: Glutamine amidotransferase class-I; Histidine biosynthesis protein; TIGRFAM: imidazole glycerol phosphate sy [...]
 
  
 0.996
ADW19459.1
COGs: COG1492 Cobyric acid synthase; InterPro IPR004459: IPR011698: IPR017929; KEGG: dal:Dalk_0453 cobyric acid synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: Cobyric acid synthase; TIGRFAM: cobyric acid synthase CobQ; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyric acid synthase CobQ.
  
 0.993
ADW19158.1
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); COGs: COG1797 Cobyrinic acid a c-diamide synthase; InterPro IPR017929: IPR011698: IPR004484; KEGG: dak:DaAHT2_1581 cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: Cobyrinic acid a,c-diamide synthase; TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyrinic acid a,c-diamide synthase.
  
 0.952
ADW18407.1
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); COGs: COG1797 Cobyrinic acid a c-diamide synthase; InterPro IPR017929: IPR004484: IPR011698; KEGG: dak:DaAHT2_1671 cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: Cobyrinic acid a,c-diamide synthase; TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyrinic acid a,c-diamide synthase.
  
 0.948
ADW17081.1
COGs: COG0141 Histidinol dehydrogenase; InterPro IPR012131: IPR001692; KEGG: dps:DP1282 histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; PRIAM: Histidinol dehydrogenase; SPTR: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase.
  
 0.912
ADW17966.1
COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496; KEGG: dps:DP2639 phosphoribosyl-AMP cyclohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase; PRIAM: Phosphoribosyl-AMP cyclohydrolase; SPTR: Phosphoribosyl-AMP cyclohydrolase; PFAM: Phosphoribosyl-AMP cyclohydrolase.
 
  
 0.910
ADW17123.1
COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807: IPR020565; KEGG: dak:DaAHT2_0351 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase.
 
  
 0.908
ADW18324.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR003099: IPR002912; KEGG: dps:DP2275 P-protein; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Prephenate dehydrogenase; SPTR: Related to P-protein; PFAM: Prephenate dehydratase; Prephenate dehydrogenase; ACT domain.
  
  
 0.891
hisG
ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
 
  
 0.876
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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