Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW19465.1Methyltransferase type 11; InterPro IPR013216; KEGG: dol:Dole_1540 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11; PFAM: Methyltransferase domain. (404 aa)    
Predicted Functional Partners:
ADW19466.1
Deoxyribodipyrimidine photo-lyase type II; COGs: COG0415 Deoxyribodipyrimidine photolyase; InterPro IPR006050: IPR005101: IPR008148; KEGG: dba:Dbac_0415 deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; SPTR: Deoxyribodipyrimidine photo-lyase; PFAM: FAD binding domain of DNA photolyase; DNA photolyase; TIGRFAM: photolyase PhrII.
 
     0.810
ADW17901.1
Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR003495: IPR012202; KEGG: dps:DP0583 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Probable hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.
   
 
 0.795
rpsJ
SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
  
 0.662
ADW18636.1
UspA domain-containing protein; InterPro IPR006016; KEGG: dak:DaAHT2_1379 UspA domain protein; PFAM: UspA domain-containing protein; SPTR: UspA; PFAM: Universal stress protein family.
  
     0.591
ADW18548.1
COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dps:DP2699 geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Probable geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase.
  
 
 0.490
ADW18720.1
Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dps:DP1743 octaprenyl-diphosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Related to octaprenyl-diphosphate synthase; PFAM: Polyprenyl synthetase.
  
 
 0.490
ADW16750.1
COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004439: IPR001804: IPR019818; KEGG: hmo:HM1_1471 isocitrate dehydrogenase, nADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; SPTR: Isocitrate dehydrogenase [NADP]; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type.
  
  
 0.478
ADW17366.1
KEGG: dat:HRM2_02180 hypothetical 5-AMP-activated protein kinase, beta-1 subunit (AMPK beta-1 chain) (AMPKb); SPTR: Hypothetical 5-AMP-activated protein kinase, beta-1 subunit (AMPK beta-1 chain) (AMPKb); PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain).
  
     0.477
ADW18722.1
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; COGs: COG0761 Penicillin tolerance protein; InterPro IPR003451; KEGG: acr:Acry_1832 hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; PRIAM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SPTR: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming).
  
  
 0.476
ADW19334.1
COGs: COG3261 Ni Fe-hydrogenase III large subunit; KEGG: dps:DP1043 hydrogenase, component E-formate hydrogenlyase subunit 5; SPTR: Related to hydrogenase, component E-formate hydrogenlyase subunit 5; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit.
    
   0.470
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (22%) [HD]