STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19470.12-dehydropantoate 2-reductase; COGs: COG1893 Ketopantoate reductase; InterPro IPR013332: IPR013752: IPR003710; KEGG: dae:Dtox_1567 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein; PRIAM: 2-dehydropantoate 2-reductase; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase. (318 aa)    
Predicted Functional Partners:
ADW19316.1
COGs: COG0413 Ketopantoate hydroxymethyltransferase; InterPro IPR003700; KEGG: hmo:HM1_2754 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; PRIAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; SPTR: 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase.
 
  
 0.934
ADW19317.1
2-dehydropantoate 2-reductase; COGs: COG1893 Ketopantoate reductase; InterPro IPR013332: IPR013752: IPR003710; KEGG: dba:Dbac_1891 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein; PRIAM: 2-dehydropantoate 2-reductase; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase.
  
  
 
0.927
ADW17235.1
COGs: COG0414 Panthothenate synthetase; InterPro IPR003721: IPR004821; KEGG: gsu:GSU1706 pantoate--beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; SPTR: Pantoate--beta-alanine ligase; TIGRFAM: pantoate/beta-alanine ligase; cytidyltransferase-related domain protein; PFAM: Pantoate-beta-alanine ligase; TIGRFAM: pantoate--beta-alanine ligase; cytidyltransferase-related domain.
    
 0.925
ADW19033.1
NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086: IPR020476: IPR020084; KEGG: gme:Gmet_0988 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain.
     0.750
ADW19471.1
COGs: COG0262 Dihydrofolate reductase; InterPro IPR001796: IPR012259: IPR017925; KEGG: gsu:GSU0571 dihydrofolate reductase; PFAM: dihydrofolate reductase region; PRIAM: Dihydrofolate reductase; SPTR: Dihydrofolate reductase; PFAM: Dihydrofolate reductase.
 
   
 0.632
ADW19474.1
Peptidase M16C associated domain protein; COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR011765: IPR007863: IPR013578; KEGG: dps:DP0121 zinc metalloprotease; PFAM: Peptidase M16C associated domain protein; peptidase M16 domain protein; SPTR: Related to zinc metalloprotease; PFAM: Peptidase M16C associated; Peptidase M16 inactive domain; Insulinase (Peptidase family M16).
       0.426
ADW19473.1
COGs: COG1490 D-Tyr-tRNAtyr deacylase; InterPro IPR003732; KEGG: dhd:Dhaf_3608 D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-tyrosyl-tRNA(Tyr) deacylase; SPTR: D-tyrosyl-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-Tyr-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase.
  
    0.411
ADW19076.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
     
 0.410
ADW19472.1
Protein of unknown function DUF558; COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: dak:DaAHT2_0521 protein of unknown function DUF558; PFAM: protein of unknown function DUF558; SPTR: Putative uncharacterized protein; PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family.
       0.410
ADW17248.1
Protein of unknown function DUF330; COGs: COG3009 conserved hypothetical protein; InterPro IPR005586; KEGG: mca:MCA0364 putative lipoprotein; PFAM: protein of unknown function DUF330; SPTR: Putative lipoprotein; PFAM: Protein of unknown function (DUF330).
  
     0.407
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.