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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW19474.1Peptidase M16C associated domain protein; COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR011765: IPR007863: IPR013578; KEGG: dps:DP0121 zinc metalloprotease; PFAM: Peptidase M16C associated domain protein; peptidase M16 domain protein; SPTR: Related to zinc metalloprotease; PFAM: Peptidase M16C associated; Peptidase M16 inactive domain; Insulinase (Peptidase family M16). (1007 aa)    
Predicted Functional Partners:
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
    
 
 0.902
ADW19473.1
COGs: COG1490 D-Tyr-tRNAtyr deacylase; InterPro IPR003732; KEGG: dhd:Dhaf_3608 D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-tyrosyl-tRNA(Tyr) deacylase; SPTR: D-tyrosyl-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-Tyr-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase.
  
    0.803
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
  0.786
ADW17427.1
COGs: COG0055 F0F1-type ATP synthase beta subunit; InterProIPR005722: IPR017691: IPR004100: IPR000194: IPR 000793: IPR003593; KEGG: cyt:cce_1512 F0F1 ATP synthase subunit beta; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase; SPTR: ATP synthase subunit B; TIGRFAM: alternate F1F0 ATPase, F1 subunit beta; ATP synthase F1, beta subunit; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; ATP synthase alpha/beta cha [...]
    
  0.778
atpD
ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
    
  0.778
ADW19472.1
Protein of unknown function DUF558; COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: dak:DaAHT2_0521 protein of unknown function DUF558; PFAM: protein of unknown function DUF558; SPTR: Putative uncharacterized protein; PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family.
       0.773
ADW17432.1
ATP synthase F0 subcomplex C subunit; InterPro IPR017708: IPR005953: IPR000454: IPR002379; KEGG: nhl:Nhal_1907 alternate F1F0 ATPase, F0 subunit C; PFAM: H+transporting two-sector ATPase C subunit; SPTR: Strongly similar to ATPE encoding subunit c of ATP synthase; TIGRFAM: alternate F1F0 ATPase, F0 subunit C; ATP synthase F0, C subunit; PFAM: ATP synthase subunit C; TIGRFAM: ATP synthase, F0 subunit c; alternate F1F0 ATPase, F0 subunit C.
   
 
 0.739
atpE
ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 
 0.739
ADW19471.1
COGs: COG0262 Dihydrofolate reductase; InterPro IPR001796: IPR012259: IPR017925; KEGG: gsu:GSU0571 dihydrofolate reductase; PFAM: dihydrofolate reductase region; PRIAM: Dihydrofolate reductase; SPTR: Dihydrofolate reductase; PFAM: Dihydrofolate reductase.
       0.583
ADW17654.1
Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475: IPR005476: IPR017871; KEGG: gur:Gura_1610 transketolase, central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase, central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
    
   0.579
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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