node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
THITE_134373 | THITE_2072748 | G2RA26 | G2QTK1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Pribosyltran domain-containing protein. | 0.510 |
THITE_134373 | THITE_2109773 | G2RA26 | G2QXY5 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.426 |
THITE_134373 | THITE_2110092 | G2RA26 | G2QRQ8 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | A_deaminase domain-containing protein. | 0.482 |
THITE_134373 | THITE_2113541 | G2RA26 | G2R3B1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.986 |
THITE_134373 | THITE_37801 | G2RA26 | G2R4U8 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.484 |
THITE_2039441 | THITE_2072748 | G2QT26 | G2QTK1 | Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | Pribosyltran domain-containing protein. | 0.601 |
THITE_2039441 | THITE_2109773 | G2QT26 | G2QXY5 | Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.490 |
THITE_2039441 | THITE_2113541 | G2QT26 | G2R3B1 | Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.557 |
THITE_2039441 | THITE_37801 | G2QT26 | G2R4U8 | Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | Uncharacterized protein. | 0.958 |
THITE_2072748 | THITE_134373 | G2QTK1 | G2RA26 | Pribosyltran domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.510 |
THITE_2072748 | THITE_2039441 | G2QTK1 | G2QT26 | Pribosyltran domain-containing protein. | Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.601 |
THITE_2072748 | THITE_2106862 | G2QTK1 | G2QRW5 | Pribosyltran domain-containing protein. | Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.542 |
THITE_2072748 | THITE_2109773 | G2QTK1 | G2QXY5 | Pribosyltran domain-containing protein. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.803 |
THITE_2072748 | THITE_2110092 | G2QTK1 | G2QRQ8 | Pribosyltran domain-containing protein. | A_deaminase domain-containing protein. | 0.532 |
THITE_2072748 | THITE_2113541 | G2QTK1 | G2R3B1 | Pribosyltran domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.537 |
THITE_2072748 | THITE_2113847 | G2QTK1 | G2R4A9 | Pribosyltran domain-containing protein. | IU_nuc_hydro domain-containing protein. | 0.636 |
THITE_2072748 | THITE_2144886 | G2QTK1 | G2R621 | Pribosyltran domain-containing protein. | Uncharacterized protein. | 0.503 |
THITE_2072748 | THITE_37801 | G2QTK1 | G2R4U8 | Pribosyltran domain-containing protein. | Uncharacterized protein. | 0.719 |
THITE_2072748 | THITE_55699 | G2QTK1 | G2R2X2 | Pribosyltran domain-containing protein. | IU_nuc_hydro domain-containing protein. | 0.636 |
THITE_2106862 | THITE_2072748 | G2QRW5 | G2QTK1 | Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. | Pribosyltran domain-containing protein. | 0.542 |