STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THITE_2115051GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (1144 aa)    
Predicted Functional Partners:
THITE_57424
GOLD domain-containing protein.
    
 
 0.957
THITE_2109458
Uncharacterized protein.
    
 0.954
THITE_2155002
Rhomboid domain-containing protein.
    
 0.954
THITE_2116949
Uncharacterized protein.
    
 0.948
THITE_2081127
Uncharacterized protein.
    
 0.942
THITE_2170323
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 0.940
THITE_2121961
Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.
    
 
 0.594
THITE_2116926
GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity.
   
  
 0.535
THITE_2080789
Mannosyltransferase.
    
 
 0.488
THITE_162029
Uncharacterized protein.
      
 0.487
Your Current Organism:
Thermothielavioides terrestris
NCBI taxonomy Id: 578455
Other names: T. terrestris NRRL 8126, Thermothielavioides terrestris NRRL 8126
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.