STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THITE_2118294NUDE_C domain-containing protein. (620 aa)    
Predicted Functional Partners:
THITE_2113624
CS domain-containing protein.
     
 0.862
PAC1
Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.
    
 
 0.807
PAC1-2
Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
    
 
 0.807
THITE_2015988
WD_REPEATS_REGION domain-containing protein.
    
 
 0.738
THITE_54770
WD_REPEATS_REGION domain-containing protein.
     
 0.647
THITE_2109567
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.629
THITE_2096446
Peptide hydrolase; Belongs to the peptidase M28 family.
    
 0.629
THITE_2121090
WD_REPEATS_REGION domain-containing protein.
    
 
 0.618
THITE_2039922
HORMA domain-containing protein.
     
 0.599
THITE_2122510
Uncharacterized protein.
    
 
 0.585
Your Current Organism:
Thermothielavioides terrestris
NCBI taxonomy Id: 578455
Other names: T. terrestris NRRL 8126, Thermothielavioides terrestris NRRL 8126
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.