STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D8PLA0_SCHCMPoly [ADP-ribose] polymerase. (787 aa)    
Predicted Functional Partners:
D8PU00_SCHCM
Poly [ADP-ribose] polymerase.
  
  
 
0.905
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.847
D8QKI4_SCHCM
Ku80-like protein.
   
 
 0.833
D8QD50_SCHCM
Ku70-like protein.
   
 
 0.802
D8PXX2_SCHCM
PAS domain-containing protein.
    
 0.746
D8PRR5_SCHCM
BRCA-2_OB1 domain-containing protein.
    
 0.729
D8PT82_SCHCM
RPA_C domain-containing protein.
    
 0.712
D8PN94_SCHCM
XPA_C domain-containing protein.
     
 0.707
D8QC41_SCHCM
Uncharacterized protein.
     
 0.706
D8PNT7_SCHCM
Uncharacterized protein.
    
 0.697
Your Current Organism:
Schizophyllum commune
NCBI taxonomy Id: 578458
Other names: S. commune H4-8, Schizophyllum commune H4-8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.