STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D8PXW7_SCHCMRibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (892 aa)    
Predicted Functional Partners:
D8PR42_SCHCM
Uncharacterized protein.
  
 0.997
D8Q7Y3_SCHCM
Uncharacterized protein.
  
 0.997
D8QDM9_SCHCM
Uncharacterized protein.
  
 0.997
D8PWE6_SCHCM
Nucleoside diphosphate kinase.
    
 0.980
D8Q3C4_SCHCM
Guanylate kinase-like domain-containing protein.
    
 0.978
D8PW93_SCHCM
Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
    
 0.977
D8PTC3_SCHCM
ADK_lid domain-containing protein; Belongs to the adenylate kinase family.
    
 0.970
ADK1
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
    
 0.970
D8PKM2_SCHCM
Uncharacterized protein.
   
 
  0.969
D8Q2T3_SCHCM
Thymidylate_kin domain-containing protein.
  
 
 0.962
Your Current Organism:
Schizophyllum commune
NCBI taxonomy Id: 578458
Other names: S. commune H4-8, Schizophyllum commune H4-8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.