STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D8QC45_SCHCMGeneral transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (400 aa)    
Predicted Functional Partners:
D8Q4H1_SCHCM
RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
   
 0.999
D8Q5I3_SCHCM
Uncharacterized protein.
    
 0.999
D8Q8P9_SCHCM
Uncharacterized protein.
   
 0.999
D8Q8Q3_SCHCM
BSD domain-containing protein.
    
 0.999
D8Q918_SCHCM
Helicase ATP-binding domain-containing protein.
    
 0.999
D8PVU7_SCHCM
RING-type domain-containing protein.
   
 0.998
D8Q0Z2_SCHCM
TFIIE beta domain-containing protein.
   
 0.997
D8QHR1_SCHCM
HTH TFE/IIEalpha-type domain-containing protein.
   
 0.997
D8Q0E6_SCHCM
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.986
D8PKL8_SCHCM
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 0.978
Your Current Organism:
Schizophyllum commune
NCBI taxonomy Id: 578458
Other names: S. commune H4-8, Schizophyllum commune H4-8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.