STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGS1ATP-dependent helicase SGS1. (451 aa)    
Predicted Functional Partners:
ANR32
Ankyrin repeat domain-containing protein 32.
  
 0.999
RFA1
Replication protein A 70 kDa DNA-binding subunit.
   
 0.991
TOP3A
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
 
 0.975
TOP3A-2
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
 
 0.975
LAMB4-2
Laminin subunit beta-4.
   
 0.975
MUS81
Crossover junction endonuclease MUS81.
   
 0.973
MUS81-2
Crossover junction endonuclease MUS81.
   
 0.973
NBO_609gi001
Double-strand break dna repair protein.
  
 0.947
NBO_65g0009
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.912
RAD50
DNA repair protein RAD50.
  
 0.910
Your Current Organism:
Nosema bombycis
NCBI taxonomy Id: 578461
Other names: N. bombycis CQ1, Nosema bombycis CQ1
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