AMAG_06056 protein (Allomyces macrogynus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

AMAG_06056

Glyco_transf_24 domain-containing protein. (259 aa)

Predicted Functional Partners:

AMAG_06723

0.767

AMAG_17524

0.731

AMAG_04405

0.649

AMAG_16207

0.649

AMAG_01267

0.644

AMAG_05457

0.644

AMAG_12123

0.639

AMAG_13210

0.630

AMAG_04383

0.615

AMAG_16227

0.615

Your Current Organism:

Allomyces macrogynus

NCBI taxonomy Id: 578462
Other names: A. macrogynus ATCC 38327, Allomyces macrogynus ATCC 38327

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMAG_01267	AMAG_04383	A0A0L0RY92	A0A0L0S8V7	Uncharacterized protein.	Uncharacterized protein.	0.865
AMAG_01267	AMAG_04405	A0A0L0RY92	A0A0L0S8E6	Uncharacterized protein.	Uncharacterized protein.	0.582
AMAG_01267	AMAG_06056	A0A0L0RY92	A0A0L0SDR5	Uncharacterized protein.	Glyco_transf_24 domain-containing protein.	0.644
AMAG_01267	AMAG_16207	A0A0L0RY92	A0A0L0TA96	Uncharacterized protein.	Uncharacterized protein.	0.582
AMAG_01267	AMAG_16227	A0A0L0RY92	A0A0L0TA34	Uncharacterized protein.	Uncharacterized protein.	0.865
AMAG_04383	AMAG_01267	A0A0L0S8V7	A0A0L0RY92	Uncharacterized protein.	Uncharacterized protein.	0.865
AMAG_04383	AMAG_04405	A0A0L0S8V7	A0A0L0S8E6	Uncharacterized protein.	Uncharacterized protein.	0.838
AMAG_04383	AMAG_05457	A0A0L0S8V7	A0A0L0SBV0	Uncharacterized protein.	Uncharacterized protein.	0.865
AMAG_04383	AMAG_06056	A0A0L0S8V7	A0A0L0SDR5	Uncharacterized protein.	Glyco_transf_24 domain-containing protein.	0.615
AMAG_04383	AMAG_16207	A0A0L0S8V7	A0A0L0TA96	Uncharacterized protein.	Uncharacterized protein.	0.838
AMAG_04405	AMAG_01267	A0A0L0S8E6	A0A0L0RY92	Uncharacterized protein.	Uncharacterized protein.	0.582
AMAG_04405	AMAG_04383	A0A0L0S8E6	A0A0L0S8V7	Uncharacterized protein.	Uncharacterized protein.	0.838
AMAG_04405	AMAG_05457	A0A0L0S8E6	A0A0L0SBV0	Uncharacterized protein.	Uncharacterized protein.	0.582
AMAG_04405	AMAG_06056	A0A0L0S8E6	A0A0L0SDR5	Uncharacterized protein.	Glyco_transf_24 domain-containing protein.	0.649
AMAG_04405	AMAG_16227	A0A0L0S8E6	A0A0L0TA34	Uncharacterized protein.	Uncharacterized protein.	0.838
AMAG_05457	AMAG_04383	A0A0L0SBV0	A0A0L0S8V7	Uncharacterized protein.	Uncharacterized protein.	0.865
AMAG_05457	AMAG_04405	A0A0L0SBV0	A0A0L0S8E6	Uncharacterized protein.	Uncharacterized protein.	0.582
AMAG_05457	AMAG_06056	A0A0L0SBV0	A0A0L0SDR5	Uncharacterized protein.	Glyco_transf_24 domain-containing protein.	0.644
AMAG_05457	AMAG_16207	A0A0L0SBV0	A0A0L0TA96	Uncharacterized protein.	Uncharacterized protein.	0.582
AMAG_05457	AMAG_16227	A0A0L0SBV0	A0A0L0TA34	Uncharacterized protein.	Uncharacterized protein.	0.865

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

30

average node degree:

5.45

avg. local clustering coefficient:

0.822

expected number of edges:

11

PPI enrichment p-value:

2.3e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050464

Nitrate reductase (NADPH) activity

2 of 2

2.91

1.31

0.0043

GO:0003735

Structural constituent of ribosome

5 of 152

1.42

1.21

0.0011

GO:0043546

Molybdopterin cofactor binding

2 of 5

2.51

1.2

0.0064

GO:0030151

Molybdenum ion binding

2 of 8

2.31

1.07

0.0107

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005763

Mitochondrial small ribosomal subunit

5 of 29

2.14

3.21

2.26e-07

GO:0005576

Extracellular region

4 of 293

1.04

0.61

0.0251

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4710

Organellar ribosome, and Plant-pathogen interaction

6 of 53

1.96

3.24

4.74e-08

CL:8987

Eukaryotic molybdopterin oxidoreductase, and Electron transport from NADPH to Ferredoxin

4 of 11

2.47

3.22

6.89e-07

CL:4769

Organellar small ribosomal subunit, and CTP metabolic process

4 of 14

2.36

3.04

1.23e-06

CL:8990

Oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor, and Eukaryotic molybdopterin oxidoreductase

3 of 5

2.69

2.67

1.15e-05

CL:4772

Organellar small ribosomal subunit, and Ribosomal protein S10

3 of 9

2.43

2.34

3.81e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

5 of 168

1.38

1.39

0.00017

map00910

Nitrogen metabolism

3 of 46

1.72

1.3

0.0019

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

5 of 252

1.21

0.83

0.0072

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005763

Mitochondrial small ribosomal subunit

4 of 26

2.09

2.24

3.26e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0274

FAD

3 of 63

1.59

0.89

0.0143

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03404

Mo-co oxidoreductase dimerisation domain

4 of 6

2.73

3.54

2.55e-07

PF00174

Oxidoreductase molybdopterin binding domain

4 of 7

2.66

3.52

2.55e-07

PF00970

Oxidoreductase FAD-binding domain

3 of 9

2.43

2.13

9.87e-05

PF00175

Oxidoreductase NAD-binding domain

3 of 16

2.18

1.81

0.00032

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR008335

Eukaryotic molybdopterin oxidoreductase

4 of 6

2.73

3.31

7.19e-07

IPR005066

Moybdenum cofactor oxidoreductase, dimerisation

4 of 6

2.73

3.31

7.19e-07

IPR000572

Oxidoreductase, molybdopterin-binding domain

4 of 6

2.73

3.31

7.19e-07

IPR036374

Oxidoreductase, molybdopterin-binding domain superfamily

4 of 7

2.66

3.29

7.19e-07

IPR014756

Immunoglobulin E-set

4 of 24

2.13

2.42

1.39e-05

(more ...)

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